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Anti-SIRP gamma Antibody (2L641)
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Catalog No. TMAY-02076
Alias SIRP γ/SIRPG, signal-regulatory protein γ, signal-regulatory protein gamma
Anti-SIRP gamma Antibody (2L641) is a Mouse antibody targeting SIRP gamma. Anti-SIRP gamma Antibody (2L641) can be used in ELISA.
Anti-SIRP gamma Antibody (2L641)
Anti-SIRP gamma Antibody (2L641)
😃Good
Catalog No. TMAY-02076Alias SIRP γ/SIRPG, signal-regulatory protein γ, signal-regulatory protein gamma
Anti-SIRP gamma Antibody (2L641) is a Mouse antibody targeting SIRP gamma. Anti-SIRP gamma Antibody (2L641) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $69 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SIRP gamma Antibody (2L641) is a Mouse antibody targeting SIRP gamma. Anti-SIRP gamma Antibody (2L641) can be used in ELISA. |
| Alias | SIRP γ/SIRPG, signal-regulatory protein γ, signal-regulatory protein gamma |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 2L641 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human SIRPG / SIRP gamma / CD172g (rh SIRPG / SIRP gamma / CD172g; TMPY-01853; NP_061026.2; Met 1-Ser 364). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Signal-regulatory protein gamma (SIRPG/SIRP gamma) also known as CD172 antigen-like family member B, CD172g, and CD172g antigen, is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPG/SIRP gamma/CD172g is a probable immunoglobulin-like cell surface receptor. On binding with CD47, SIRPG can mediate cell-cell adhesion. SIRPG/SIRP gamma is engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. SIRPG/SIRP gamma/CD172g is detected in liver, and at very low levels in brain, heart, lung, pancreas, kidney, placenta and skeletal muscle. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells. This cytokine is mainly present in the paracortical T-cell area of lymph nodes, with only sparse positive cells in the mantle and in the germinal center of B-cell follicles. In the thymus, SIRPG is primarily expressed in the medulla on mature T-lymphocytes that have undergone thymic selection. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human SIRPG / SIRP gamma / CD172g protein (TMPY-01853) |
| Antigen Species | Human |
| Biology Area | Phosphatases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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