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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Aminooxy-PEG1-propargyl is a PEG-based linker for PROTACs, facilitating the combination of two essential ligands crucial for PROTAC molecule formation. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands linked together: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. These molecules leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 115.13 |
Formula | C5H9NO2 |
Cas No. | 1895922-69-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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