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N-Methylnicotinamide is one of the endogenous metabolites that ameliorates endothelial dysfunction.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $117 | In Stock | In Stock | |
| 5 mg | $289 | In Stock | In Stock | |
| 10 mg | $428 | In Stock | In Stock | |
| 25 mg | $698 | In Stock | In Stock | |
| 50 mg | $968 | - | In Stock | |
| 100 mg | $1,280 | - | In Stock | |
| 200 mg | $1,760 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $262 | In Stock | In Stock |
| Description | N-Methylnicotinamide is one of the endogenous metabolites that ameliorates endothelial dysfunction. |
| In vitro | To this aim, 7- and 30-day-old plants were treated with 0, 120, 240, 500, and 1,000 μM Pb during 10 days. The content of Medicarpin was determined by HPLC, and the extent of Medicarpin production was deduced from the result of semiquantitative RT-PCR performed on PAL, CHS, and VR genes. HPLC results indicated that Medicarpin concentration has been reduced in the roots, while its exudation to the culture medium has been increased. RT-PCR results indicated that the transcript levels of PAL, CHS, and VR genes have not been affected following Pb stress in seedlings. At the vegetative stage, transcript levels of PAL and CHS genes have been reduced in the roots. However, the transcript level of VR gene increased at 120 and 240 μM Pb, while it decreased at higher concentrations. In the shoot, the transcript levels of PAL, CHS, and VR genes were increased following increased concentration of lead in the medium[1] |
| Synonyms | (-)-Medicarpin |
| Molecular Weight | 270.28 |
| Formula | C16H14O4 |
| Cas No. | 32383-76-9 |
| Smiles | [H][C@@]12COc3cc(O)ccc3[C@]1([H])Oc1cc(OC)ccc21 |
| Relative Density. | 1.319g/cm3 |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 22.5 mg/mL (83.25 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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