SEMA7A Protein, Mouse, Recombinant (His)

Name: SEMA7A Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPK-01216
Price: 43 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Semaphorin-L, Semaphorin-K1, Semaphorin-7A, SEMAL, SEMAK1, Sema7A, Sema L, MGC126692, JMH, H-Sema-L, H-SEMA-K1, CDw108, CD108MGC126696, CD108) Copy Product Info

Synonyms: Semaphorin-L, Semaphorin-K1, Semaphorin-7A, SEMAL, SEMAK1, Sema7A, Sema L, MGC126692, JMH, H-Sema-L, H-SEMA-K1, CDw108, CD108MGC126696, CD108

Catalog No. TMPK-01216 Copy Product Info

SEMA7A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is Q9QUR8.

Pack Size	Price	USA Stock	Global Stock
5 µg	$43	-	In Stock
10 µg	$66	-	In Stock
20 µg	$105	-	In Stock
50 µg	$197	-	In Stock
100 µg	$336	-	In Stock
200 µg	$596	7-10 days	7-10 days
500 µg	$1,350	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 95% as determined by Bis-Tris PAGE > 90% as determined by HPLC

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	SEMA7A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is Q9QUR8.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q9QUR8
Construction	Gln45-Ala646
Protein Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 200 mM L-arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Semaphorin-L, Semaphorin-K1, Semaphorin-7A, SEMAL, SEMAK1, Sema7A, Sema L, MGC126692, JMH, H-Sema-L, H-SEMA-K1, CDw108, CD108MGC126696, CD108
Research Background	Semaphorin7A (Sema7A) plays an important role in the immunoregulation of the brain.Sema7A is upregulated in the epileptic brain and plays a potential role in the regulation of seizure activity in PTZ-kindled epileptic rats, which may be related to neuroinflammation. Sema7A promotes the inflammatory cytokines TNF-α and IL-6 as well as the growth of mossy fibers through the ERK pathway, suggesting that Sema7A may promote seizures by increasing neuroinflammation and activating pathological neural circuits. Sema7A plays a critical role in epilepsy and could be a potential therapeutic target for this neurological disorder.

Chemical Properties

Molecular Weight

69.5 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.