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Anti-CRB2 Polyclonal Antibody
(Synonyms: RP11-230L22.2, Crumbs-like protein 2, Crumbs homolog 2(Drosophila), Crumbs homolog 2, CRUM2, Crb2) Copy Product Info
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Synonyms: RP11-230L22.2, Crumbs-like protein 2, Crumbs homolog 2(Drosophila), Crumbs homolog 2, CRUM2, Crb2
Catalog No. TMAB-00476 Copy Product Info
🥰Excellent
Anti-CRB2 Polyclonal Antibody is a Rabbit antibody targeting CRB2. Anti-CRB2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-CRB2 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-CRB2 Polyclonal Antibody is a Rabbit antibody targeting CRB2. Anti-CRB2 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | RP11-230L22.2, Crumbs-like protein 2, Crumbs homolog 2(Drosophila), Crumbs homolog 2, CRUM2, Crb2 |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted and Cell membrane. |
| Tissue Specificity | Expressed in retina, fetal eye and brain. Also expressed in kidney, ARPE-19 and RPE/choroid cell lines, and at low levels in lung, placenta, and heart. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | CRB2 is a 1,285 amino acid protein that contains three laminin G-like domains and 15 EGF-like domains and exists as multiple alternatively spliced isoforms that are either secreted or membrane bound. Expressed in kidney and retina, as well as in fetal eye and brain, CRB2 is thought to play a role in the morphogenesis of polarized cells and may be involved in DNA repair. Defects in the gene encoding CRB2 are associated with the pathogenesis of autosomal recessive retinitis pigmentosa (RP) and Leber congenital amaurosis (LCA), the former of which refers to a group of diseases that lead to the degeneration of retinal photoreceptor cells, ultimately resulting in a loss of vision. The gene encoding CRB2 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome. |
| Immunogen | KLH conjugated synthetic peptide: human CRB2 |
| Antigen Species | Human |
| Gene Name | CRB2 |
| Gene ID | |
| Protein Name | Protein crumbs homolog 2 |
| Uniprot ID | |
| Biology Area | Other Antibodies |
| Function | May play a role in polarized cells morphogenesis. |
| Molecular Weight | Theoretical: 100, 123, 131 kDa. Actual: 100-135 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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