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Anti-GPR183 Polyclonal Antibody
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Catalog No. TMAB-00791
Alias Lymphocyte specific G protein coupled receptor, G-protein coupled receptor 183, GP183, Epstein-Barr virus-induced G-protein coupled receptor 2, Epstein-Barr virus-induced gene 2, ebv-induced gene 2, EBV induced G protein coupled receptor 2, EBI2, ebi 2
Anti-GPR183 Polyclonal Antibody is a Rabbit antibody targeting GPR183. Anti-GPR183 Polyclonal Antibody can be used in ELISA,WB.
Anti-GPR183 Polyclonal Antibody
Anti-GPR183 Polyclonal Antibody
😃Good
Catalog No. TMAB-00791Alias Lymphocyte specific G protein coupled receptor, G-protein coupled receptor 183, GP183, Epstein-Barr virus-induced G-protein coupled receptor 2, Epstein-Barr virus-induced gene 2, ebv-induced gene 2, EBV induced G protein coupled receptor 2, EBI2, ebi 2
Anti-GPR183 Polyclonal Antibody is a Rabbit antibody targeting GPR183. Anti-GPR183 Polyclonal Antibody can be used in ELISA,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-GPR183 Polyclonal Antibody is a Rabbit antibody targeting GPR183. Anti-GPR183 Polyclonal Antibody can be used in ELISA,WB. |
| Synonyms | Lymphocyte specific G protein coupled receptor, G-protein coupled receptor 183, GP183, Epstein-Barr virus-induced G-protein coupled receptor 2, Epstein-Barr virus-induced gene 2, ebv-induced gene 2, EBV induced G protein coupled receptor 2, EBI2, ebi 2 |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | Sample: Lane 1: Mouse LympHnode tissue lysates Lane 2: Mouse Spleen tissue lysates Lane 3: Mouse Lung tissue lysates Lane 4: Rat LympHnode tissue lysates Lane 5: Rat Spleen tissue lysates Lane 6: Rat Lung tissue lysates Lane 7: Human HeLa cell lysates Lane 8: Human Jurkat cell lysates Lane 9: Human Raji cell lysates Lane 10: Human K562 cell lysates Lane 11: Human A549 cell lysates Primary: Anti-GPR183 (TMAB-00791) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 41 kDa Observed band size: 38 kDa  |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Tissue Specificity | Expressed abundantly in lymphoid tissues such as spleen and lymph node, and in B- and T-lymphocytes. Also highly expressed in lung, heart and gastrointestinal tract, and weakly expressed in the urogenital system and brain. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Epstein-Barr virus-induced gene 2 is a 357 amino acid multi pass membrane protein. It is expressed in B-lymphocytes and lymphoid tissues and may function in the modulation of the immune system. Out of the nine genes that are induced by the Epstein-Barr virus, Ebi2 exhibits the highest levels of up-regulation. Ebi2 is a G-protein coupled receptor that signals through the G-protein Gαi. Ebi2 contains seven hydrophobic transmembrane regions and a putative N-linked glycosylation site at its extracellular N-terminus. Ebi2 is believed to be involved in regulating the effects of the Epstein-Barr virus on B-lymphocytes. In addition, Ebi2 may play a role mediating normal lymphocyte functions. |
| Immunogen | KLH conjugated synthetic peptide: human EBV Induced Gene 2 |
| Antigen Species | Human |
| Gene Name | GPR183 |
| Gene ID | |
| Protein Name | G-protein coupled receptor 183 |
| Uniprot ID | |
| Function | Orphan receptor that plays a central role during humoral immunity. Promotes activated B-cell localization in the outer follicle and interfollicular regions. Its specific expression during B-cell maturation helps position B-cells appropriately for mounting T-dependent antibody responses (By similarity). Signals constitutively through G(i)-alpha, but not G(s)-alpha or G(q)-alpha. |
| Molecular Weight | Theoretical: 41 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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