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Anti-PEDF Antibody (9F493)

😃Good
Catalog No. TMAY-03840
Alias serpin peptidase inhibitor, clade F,member 1, PIG35, PEDF, OI6, OI12, EPC-1

Anti-PEDF Antibody (9F493) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (9F493) can be used in ELISA.

Anti-PEDF Antibody (9F493)

Anti-PEDF Antibody (9F493)

😃Good
Catalog No. TMAY-03840Alias serpin peptidase inhibitor, clade F,member 1, PIG35, PEDF, OI6, OI12, EPC-1
Anti-PEDF Antibody (9F493) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (9F493) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-PEDF Antibody (9F493) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (9F493) can be used in ELISA.
Aliasserpin peptidase inhibitor, clade F,member 1, PIG35, PEDF, OI6, OI12, EPC-1
Ig Type
Monoclonal Rabbit IgG
Clone
9F493
Reactivity
Rat
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Rat SerpinF1/PEDF (rR SerpinF1/PEDF; TMPY-00266; NP_808788.1; Met1-Thr418).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundPigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. PEDF does not inhibit either serine or cysteine proteinases. PEDF exerts diverse physiological activities including anti-angiogenesis, anti-vasopermeability, anti-tumor, and neurotrophic activities. PEDF acts via multiple high affinity ligands and cell receptors. It has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. PEDF induces macrophages apoptosis and necrosis through the activation of peroxisome proliferator-activated receptor-gamma by which PEDF could modulate inflammatory reactions in septic shock. It balances angiogenesis in the eye and blocks tumor progression.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Rat SerpinF1/PEDF Protein (TMPY-00266)
Antigen Species
Rat
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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