Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-PEDF Antibody (9F493) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (9F493) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-PEDF Antibody (9F493) is a Rabbit antibody targeting PEDF. Anti-PEDF Antibody (9F493) can be used in ELISA. |
Alias | serpin peptidase inhibitor, clade F,member 1, PIG35, PEDF, OI6, OI12, EPC-1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9F493 |
Reactivity | Rat |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat SerpinF1/PEDF (rR SerpinF1/PEDF; TMPY-00266; NP_808788.1; Met1-Thr418). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Pigment epithelium-derived factor, also known as PEDF, Serpin F1, and SERPINF1, is a multiple functional protein that has both anti-angiogenic activity and neurotrophic activity at the same time. PEDF is a secreted glycoprotein that belongs to the noninhibitory serpin. It has an alpha/beta core serine-protease inhibitor domain, three major beta-sheets, and ten alpha-helices. PEDF does not inhibit either serine or cysteine proteinases. PEDF exerts diverse physiological activities including anti-angiogenesis, anti-vasopermeability, anti-tumor, and neurotrophic activities. PEDF acts via multiple high affinity ligands and cell receptors. It has been described as a natural angiogenesis inhibitor with neurotrophic and immune-modulation properties. PEDF induces macrophages apoptosis and necrosis through the activation of peroxisome proliferator-activated receptor-gamma by which PEDF could modulate inflammatory reactions in septic shock. It balances angiogenesis in the eye and blocks tumor progression. |
Conjucates | Unconjugated |
Immunogen | Recombinant Rat SerpinF1/PEDF Protein (TMPY-00266) |
Antigen Species | Rat |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.