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MRGPRX1 agonist 1

Name: MRGPRX1 agonist 1
Brand: TargetMol
SKU: T12104
Price: 90 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12104Cas No. 2377379-39-8

MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1) with an EC50 of 50 nM.

MRGPRX1 agonist 1

🥰Excellent

Purity: 99.95%

Catalog No. T12104Cas No. 2377379-39-8

MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1) with an EC50 of 50 nM.

Pack Size	Price	Availability
1 mg	$90	In Stock
5 mg	$222	In Stock
10 mg	$355	In Stock
25 mg	$645	In Stock
50 mg	$883	In Stock
100 mg	$1,260	In Stock
1 mL x 10 mM (in DMSO)	$245	In Stock

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Batch Information

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Purity:99.95%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	MRGPRX1 agonist 1 is a highly potent agonist of MRGPRX1 (Mas-related G-protein-coupled receptor X1) with an EC50 of 50 nM.
Targets&IC50	MRGPRX1:50 nM(EC50)

Chemical Properties

Molecular Weight	435.5
Formula	C₂₃H₂₁N₃O₄S
Cas No.	2377379-39-8
Smiles	COc1ccccc1S(=O)(=O)Nc1ccc(C)cc1Oc1ccc2c(N)nccc2c1
Relative Density.	1.365 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (287.03 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2962 mL	11.4811 mL	22.9621 mL	114.8106 mL
5 mM	0.4592 mL	2.2962 mL	4.5924 mL	22.9621 mL
10 mM	0.2296 mL	1.1481 mL	2.2962 mL	11.4811 mL
20 mM	0.1148 mL	0.5741 mL	1.1481 mL	5.7405 mL
50 mM	0.0459 mL	0.2296 mL	0.4592 mL	2.2962 mL
100 mM	0.0230 mL	0.1148 mL	0.2296 mL	1.1481 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc