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Anti-CLPS Antibody (5Z220)
😃Good
Catalog No. TMAY-02611
Alias colipase, pancreatic
Anti-CLPS Antibody (5Z220) is a Mouse antibody targeting CLPS. Anti-CLPS Antibody (5Z220) can be used in IHC-P.
Anti-CLPS Antibody (5Z220)
Anti-CLPS Antibody (5Z220)
😃Good
Catalog No. TMAY-02611Alias colipase, pancreatic
Anti-CLPS Antibody (5Z220) is a Mouse antibody targeting CLPS. Anti-CLPS Antibody (5Z220) can be used in IHC-P.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Mouse Monoclonal Application: IHC-P Reactivity: Human |
| Alias | colipase, pancreatic |
| Ig Type | Mouse IgG1 |
| Clone | 5Z220 |
| Reactivity | Human |
| Verified Activity | Immunochemical staining of human CLPS in human pancreas with mouse monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:100-1:500 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This product is a recombinant monoclonal antibody expressed from HEK293 cells. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Colipase belongs to the colipase family. Structural studies of the complex and of colipase alone have revealed the functionality of its architecture. It is a small protein with five conserved disulphide bonds. Structural analogies have been recognised between a developmental protein, the pancreatic lipase C-terminal domain, the N-terminal domains of lipoxygenases and the C-terminal domain of alpha-toxin. Colipase can only be detected in pancreatic acinar cells, suggesting regulation of expression by tissue-specific elements. Colipase allows lipase to anchor noncovalently to the surface of lipid micelles, counteracting the destabilizing influence of intestinal bile salts. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase. Colipase is a cofactor needed by pancreatic lipase for efficient dietary lipid hydrolysis. It binds to the C-terminal, non-catalytic domain of lipase, thereby stabilising as active conformation and considerably increasing the overall hydrophobic binding site. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CLPS Protein (TMPY-02846) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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