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Pascolizumab

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Catalog No. T77426Cas No. 331243-22-2
Alias SB-240683

Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis.

Pascolizumab

Pascolizumab

😃Good
Catalog No. T77426Alias SB-240683Cas No. 331243-22-2
Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$228-In Stock
5 mg$589-In Stock
10 mg$959-In Stock
25 mg$1,420-In Stock
50 mg$1,920-In Stock
100 mg$2,590-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis.
Targets&IC50
Tonsillar B cells:377 pM, T cells:157pM
In vitro
Pascolizumab binds to IL-4 and inhibits the interaction between IL-4 and its receptor alpha chain[1].
Pascolizumab (0-10000 pM; 3 days) demonstrates anti-proliferative activity with IC50 values of 157 pM for T cells and 377 pM for tonsillar B cells[1].
SynonymsSB-240683
Reactivity
Human
Verified Activity
Immobilized Human IL-4 Protein (His) at 2 μg/mL (30 μL/well) can bind Pascolizumab. The EC50 is 88.83 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-4
Chemical Properties
Molecular Weight147.18 kDa
Cas No.331243-22-2
Antibody Information
IsotypeHuman IgG1 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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