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Pascolizumab
(Synonyms: SB-240683) Copy Product Info
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Synonyms: SB-240683
Catalog No. T77426 Copy Product Info
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Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis.
Cas No. 331243-22-2
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $228 | - | In Stock | |
| 5 mg | $589 | - | In Stock | |
| 10 mg | $959 | - | In Stock | |
| 25 mg | $1,420 | - | In Stock | |
| 50 mg | $1,920 | - | In Stock | |
| 100 mg | $2,590 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
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Antigen Details
Chemical Properties
Antibody Information
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| Description | Pascolizumab (SB-240683) is a humanized monoclonal antibody targeting IL-4, exhibiting asthmatic effects and useful for studying allergic rhinitis. |
| Targets & IC50 | Tonsillar B cells:377 pM, T cells:157pM |
| In vitro | Pascolizumab binds to IL-4 and inhibits the interaction between IL-4 and its receptor alpha chain[1]. Pascolizumab (0-10000 pM; 3 days) demonstrates anti-proliferative activity with IC50 values of 157 pM for T cells and 377 pM for tonsillar B cells[1]. |
| Endotoxin | <1.0 EU/mg |
| Synonyms | SB-240683 |
| Reactivity | Human |
| Verified Activity | Immobilized Human IL-4 Protein (His) at 2 μg/mL (30 μL/well) can bind Pascolizumab. The EC50 is 88.83 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-4 |
| Molecular Weight | 147.18 kDa |
| Cas No. | 331243-22-2 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: Pascolizumab chemical structure | Pascolizumab in vitro | Pascolizumab molecular weight
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