IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated

Name: IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated
Brand: TargetMol
SKU: TMPK-00165
Rating: 4.5 (1 reviews)

(Synonyms: TCGFR, p55, IL2RA, IL2R, IL-2 R α/CD25, IL-2 R α, IL-2 R alpha, IDDM10, CD25) Copy Product Info

Synonyms: TCGFR, p55, IL2RA, IL2R, IL-2 R α/CD25, IL-2 R α, IL-2 R alpha, IDDM10, CD25

Catalog No. TMPK-00165 Copy Product Info

Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.6 kDa and the accession number is P01589.

IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated

Pack Size	Price	USA Stock	Global Stock
5 µg	$91	7-10 days	7-10 days
10 µg	$148	7-10 days	7-10 days
20 µg	$245	7-10 days	7-10 days
50 µg	$483	7-10 days	7-10 days
100 µg	$813	7-10 days	7-10 days
200 µg	$1,470	7-10 days	7-10 days
500 µg	$3,250	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized Anti-CD25 Antibody, hFc Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-2 R alpha, His Tag with the EC50 of 11.9ng/ml determined by ELISA.
Description	Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells. IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.6 kDa and the accession number is P01589.
Species	Human
Expression System	HEK293 Cells
Tag	C-His-Avi
Accession Number	P01589
Construction	Glu22-Cys213
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	TCGFR, p55, IL2RA, IL2R, IL-2 R α/CD25, IL-2 R α, IL-2 R alpha, IDDM10, CD25
Research Background	Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL‑2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

Chemical Properties

Molecular Weight

24.6 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

IDDM-10IDDM 10CD-25CD 25

Related Tags: IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated chemical structure | IL-2 R alpha/CD25 Protein, Human, Recombinant (His & Avi), Biotinylated molecular weight