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sFTX-3.3
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Catalog No. T38854Cas No. 141997-14-0
sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.
sFTX-3.3
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Catalog No. T38854Cas No. 141997-14-0
sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $970 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively. |
| Targets&IC50 | Ca2+ channel, N-type:0.70 mM (IC50), Ca2+ channel, P-type:0.24 mM (IC50) |
| In vitro | sFTX-3.3 (100 μM) notably moderates presynaptic calcium and sodium currents, diminishing the slow component duration of the former by approximately 50% and the latter by roughly 20% in comparison to control levels. Additionally, it decreases whole-cell sodium current in SK.N.SH cells by about 15%[3]. |
| Molecular Weight | 287.412 |
| Formula | C12H29N7O |
| Cas No. | 141997-14-0 |
| Relative Density. | 1.28 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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