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Synonyms: PMKASE, PMKA, PMK, phosphomevalonate kinase, HUMPMKI
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $268 | 7-10 days | 7-10 days |
| Description | Anti-PMVK Antibody (7Y287) is a Rabbit antibody targeting PMVK. Anti-PMVK Antibody (7Y287) can be used in ELISA,IP,WB. |
| Synonyms | PMKASE, PMKA, PMK, phosphomevalonate kinase, HUMPMKI |
| Ig Type | Rabbit IgG |
| Clone | 7Y287 |
| Reactivity | Human |
| Specificity | Human PMVK |
| Application | |
| Recommended Dose | WB: 1:500-1:1000; ELISA: 1:25000-1:50000; IP: 0.2-1 μL/mg of lysate |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human PMVK / phosphomevalonate kinase (rh PMVK / phosphomevalonate kinase; TMPY-04767; Q15126; Met1-Leu192). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human PMVK / phosphomevalonate kinase Protein (TMPY-04767) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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