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PPIH Protein, Human, Recombinant (His)

Catalog No. TMPJ-00676
Synonyms: Peptidyl-Prolyl Cis-Trans Isomerase H, Rotamase H, PPIase H, Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H, CypH, PPIH, U-snRNP-Associated Cyclophilin SnuCyp-20, CYP20, USA-CYP

Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.

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PPIH Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
10 μg 5 days $ 184.00
50 μg 5 days $ 545.00
500 μg 5 days $ 1,900.00
1 mg 5 days $ 2,730.00
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Biological Description
Technical Params
Product Properties
Description Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.
Species Human
Expression System E. coli
Tag N-6His
Accession Number O43447
Synonyms Peptidyl-Prolyl Cis-Trans Isomerase H, Rotamase H, PPIase H, Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H, CypH, PPIH, U-snRNP-Associated Cyclophilin SnuCyp-20, CYP20, USA-CYP
Amino Acid Met1-Met177
Construction Recombinant Human Peptidyl-Prolyl Cis-Trans Isomerase H is produced by our E.coli expression system and the target gene encoding Met1-Met177 is expressed with a 6His tag at the N-terminus.
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Molecular Weight 24 KDa, reducing conditions
Endotoxin Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
Stability & Storage

Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Shipping

The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

Research Background Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.

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Keywords

PPIH Protein, Human, Recombinant (His) Peptidyl-Prolyl Cis-Trans Isomerase H CYP-20 Rotamase H PPIase H Small Nuclear Ribonucleoprotein Particle-Specific Cyclophilin H CypH PPIH U-snRNP-Associated Cyclophilin SnuCyp-20 CYP 20 CYP20 USA-CYP recombinant recombinant-proteins proteins protein

 

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