CD59 regulates complement activation cascade at the final step, inhibiting formation of membrane attack complex (MAC). This protein, being anchored to the cell membrane via glycosyl phosphatidyl inositol (GPI), is expressed ubiquitously on cells which are in contact with body fluids containing components.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
100 μg | 5 days | $ 418.00 | |
500 μg | 5 days | $ 1,670.00 | |
1 mg | 5 days | $ 2,800.00 |
Description | CD59 regulates complement activation cascade at the final step, inhibiting formation of membrane attack complex (MAC). This protein, being anchored to the cell membrane via glycosyl phosphatidyl inositol (GPI), is expressed ubiquitously on cells which are in contact with body fluids containing components. |
Species | Human |
Expression System | HEK293 |
Tag | C-hFc |
Accession Number | P13987-1 |
Synonyms | CD59, HRF20, MACIF, MIN1, MIC11, MAC-IP, MIN3, MIN2, HRF-20, MEM43, MACIP, MSK21, G344, 1F5, MIRL |
Construction | Recombinant Human CD59 Protein is expressed from HEK293 with hFc tag at the C-Terminus. It contains Leu26-Asn102.[Accession |P13987-1] |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
Molecular Weight | The protein has a predicted MW of 35.73 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result. |
Endotoxin | Less than 1EU per μg by the LAL method. |
Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability & Storage |
-20 to -80°C for 12 months as supplied from date of receipt. -20 to -80°C for 3-6 months in unopened state after reconstitution. 2-8°C for 2-7 days after reconstitution. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | CD59 regulates complement activation cascade at the final step, inhibiting formation of membrane attack complex (MAC). This protein, being anchored to the cell membrane via glycosyl phosphatidyl inositol (GPI), is expressed ubiquitously on cells which are in contact with body fluids containing components. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CD59 Protein, Human, Recombinant (hFc) CD59 HRF20 MIN 2 CD-59 MACIF G-344 MIN-2 CD 59 MIN1 MIC-11 MIC11 MIN-1 G 344 MAC-IP HRF 20 MSK-21 MIN-3 MIN3 MIN2 HRF-20 MEM43 MIN 3 MSK 21 MACIP MEM-43 MIN 1 MSK21 MEM 43 MIC 11 G344 1F5 MIRL recombinant recombinant-proteins proteins protein