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Anti-SIRP beta 1 Antibody (4S571) (Synonyms: SIRP-β/Sirpb1a, SIRP-β, SIRP-beta, Sirpb1a, Sirpb1, Sirpb, 99...)

Catalog No. TMAY-03477 Copy Product Info
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Anti-SIRP beta 1 Antibody (4S571) is a Rabbit antibody targeting SIRP beta 1. Anti-SIRP beta 1 Antibody (4S571) can be used in ELISA.

Anti-SIRP beta 1 Antibody (4S571)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03477
Synonyms SIRP-β/Sirpb1a, SIRP-β, SIRP-beta, Sirpb1a, Sirpb1, Sirpb, 99327N5Rik

Anti-SIRP beta 1 Antibody (4S571) is a Rabbit antibody targeting SIRP beta 1. Anti-SIRP beta 1 Antibody (4S571) can be used in ELISA.

Anti-SIRP beta 1 Antibody
(4S571)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2687-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-SIRP beta 1 Antibody (4S571) is a Rabbit antibody targeting SIRP beta 1. Anti-SIRP beta 1 Antibody (4S571) can be used in ELISA.
SynonymsSIRP-β/Sirpb1a, SIRP-β, SIRP-beta, Sirpb1a, Sirpb1, Sirpb, 99327N5Rik
Ig Type
Rabbit IgG
Clone
4S571
Reactivity
Mouse
Specificity
Mouse SIRP-beta/Sirpb1a
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse SIRPB1A (rM SIRPB1A; TMPY-02388; BAD26610.1; Met1-Lys363).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSIRPB1A (Signal-regulatory protein beta 1A), also known as SIRP beta 1, belongs to signal-regulatory-protein (SIRP) family, and immunoglobulin superfamily. Signal-regulatory proteins (SIRPs) are cell-surface glycoproteins expressed on myeloid and neural cells that have been shown to recruit SH2 domain-containing protein phosphatase 1 (SHP-1) and SHP-2 and to regulate receptor tyrosine kinase-coupled signaling. SIRP are classified as SIRP alpha molecules, containing 11- to 113-amino acid long, or SIRP beta molecules, with a 5-amino acid long intracytoplasmic domain. SIRP beta 1 is a new DAP12-associated receptor involved in the activation of myeloid cells, which contains a short cytoplasmic domain that lacks sequence motifs capable of recruiting SHP-1 and SHP-2. SIRP beta 1 acts as an activating isoform of SIRP alpha molecules, confirming the co-existence of inhibitory ITIM-bearing molecules, recruiting SHP-1 and SHP-2 protein tyrosine phosphatases, and activating counterparts, whose engagement couples to protein tyrosine kinases via ITAM-bearing molecules.s
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Mouse SIRPB1A protein (TMPY-02388)
Antigen Species
Mouse
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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