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TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

NPS ALX Compound 4a

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Catalog No. T12262Cas No. 299433-10-6

NPS ALX Compound 4a is a potent and selective antagonist of the 5-HT6 receptor with an IC50 of 7.2 nM.

NPS ALX Compound 4a
Other Forms of NPS ALX Compound 4a:

NPS ALX Compound 4a

😃Good
Catalog No. T12262Cas No. 299433-10-6
NPS ALX Compound 4a is a potent and selective antagonist of the 5-HT6 receptor with an IC50 of 7.2 nM.
Pack SizePriceAvailabilityQuantity
25 mgInquiry1-2 weeks
50 mgInquiry1-2 weeks
100 mgInquiry1-2 weeks
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Product Introduction

Bioactivity
Description
NPS ALX Compound 4a is a potent and selective antagonist of the 5-HT6 receptor with an IC50 of 7.2 nM.
Targets&IC50
5-HT6 receptor:0.2 nM (ki), 5-HT6 receptor:7.2 nM
Chemical Properties
Molecular Weight431.55
FormulaC25H25N3O2S
Cas No.299433-10-6
Relative Density.1.36 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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2 Enter the in vivo formulation:
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Keywords

NPS ALX Compound 4a5HTReceptor5-HT6 Receptor5HT Receptor
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