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DPNB-ABT594
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Catalog No. T72982
DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates nAChRs containing α4β2 subunits over the α7 subunit. It is utilized to map the distribution of nAChRs on medial habenula (MHb) neurons, thereby facilitating a deeper understanding of nAChR-mediated Ca2+ signaling in the MHb [1].
DPNB-ABT594
😃Good
Catalog No. T72982
DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates nAChRs containing α4β2 subunits over the α7 subunit. It is utilized to map the distribution of nAChRs on medial habenula (MHb) neurons, thereby facilitating a deeper understanding of nAChR-mediated Ca2+ signaling in the MHb [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,670 | 6-8 weeks | |
| 50 mg | $2,180 | 6-8 weeks | |
| 100 mg | $2,800 | 6-8 weeks |
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Chemical Properties
| Description | DPNB-ABT594, a nitrobenzyl-caged ABT594, selectively activates nAChRs containing α4β2 subunits over the α7 subunit. It is utilized to map the distribution of nAChRs on medial habenula (MHb) neurons, thereby facilitating a deeper understanding of nAChR-mediated Ca2+ signaling in the MHb [1]. |
| Molecular Weight | 672.16 |
| Formula | C31H46ClN3O11 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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