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TargetMol | Compound Library

Anti-Fungal Compound Library

Catalog No. L4500

Invasive fungal infections are a significant health problem in immunocompromised patients. However, the number of therapeutic options for the treatment of invasive fungal infections is quite limited, and include only three structural classes of drugs: polyenes, azoles, and echinocandins. Anti-fungi compound library from TargetMol is a unique collection of 425 compounds that include natural product (polyene and echinocandins), target specific chemicals (azoles) and FDA approved antifungal agents.More recently, interest in natural product-based screening has enjoyed a renaissance. This has been driven not only by the recognition of the valuable features of natural product hits and that natural substances have evolved over a very long selection process to form optimal interactions with biological macromolecules, but by improvements in structure-identification, separation, and target identification. Recently, broad interest in combination screening to identify molecules that synergize with existing classes of antibacterial and antifungal drugs as an approach to improve efficacy has emerged. Our anti-fungi compound library is an effective tool for drug repurposing screening and combination screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L4500

Anti-Fungal Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 425 antifungal compounds effective for drug repurposing screening, combination screening and biological investigation.
  • Contains antifungal agents to treat tinea corporis and Candidiasis, and compounds inhibiting the fungal-specific targets.
  • Bioactivity and safety confirmed by clinical research and trials, some of which are FDA approved;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Antifungal
Antibacterial
Antibiotic
Apoptosis
Endogenous Metabolite
Parasite
Autophagy
Cytochromes P450
Anti-infection
Antioxidant
Influenza Virus
Antifection
Reactive Oxygen Species
COX
Phosphatase
Virus Protease
DNA/RNA Synthesis
NF-κB
Ferroptosis
PKC
Topoisomerase
Mitochondrial Metabolism
ATPase
HIV Protease
Dopamine Receptor
p38 MAPK
Dehydrogenase
Calcium Channel
MAO
Hedgehog/Smoothened
HSV
MMP
Lipoxygenase
Potassium Channel
Sodium Channel
Microtubule Associated
HCV Protease
Estrogen/progestogen Receptor
NADPH
Histamine Receptor
JNK
Mitophagy
PKA
PPAR
Wnt/beta-catenin
VEGFR
Caspase
Glucocorticoid Receptor
JAK
IL Receptor
Cholinesterase (ChE)
Antiviral
ribosome
Phospholipase
5-HT Receptor
TNF
AChR
Tyrosinase
AhR
Advanced Glycation End Products
Proton pump
MicroRNA
NOS
Carbonic Anhydrase
Src
Integrin
CRM1
Arginase
LTR
HBV
Estrogen Receptor/ERR
Serine Protease
Nucleoside Antimetabolite/Analog
ERK
Amylase
Aryl Hydrocarbon Receptor
IRE1
Myosin
E1/E2/E3 Enzyme
UGT
Gamma-secretase
NMDAR
Monoamine Transporter
ROS
Opioid Receptor
Fatty Acid Synthase
FAAH
CaMK
DNA
mTOR
Androgen Receptor
Interleukin
HSP
Free radical scavengers
Sirtuin
Bcl-2 Family
Nrf2
RSV
IκB/IKK
Reverse Transcriptase
STAT
GABA Receptor
Hydroxylase
Platelet aggregation
NADPH-oxidase
NOD
Ras
p53
NO Synthase
Monoamine Oxidase
ADC Cytotoxin

Keywords