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TargetMol | Compound Library

Anti-Fungal Compound Library

Catalog No. L4500

Invasive fungal infections are a significant health problem in immunocompromised patients. However, the number of therapeutic options for the treatment of invasive fungal infections is quite limited, and include only three structural classes of drugs: polyenes, azoles, and echinocandins. Anti-fungi compound library from TargetMol is a unique collection of 535 compounds that include natural product (polyene and echinocandins), target specific chemicals (azoles) and FDA approved antifungal agents.More recently, interest in natural product-based screening has enjoyed a renaissance. This has been driven not only by the recognition of the valuable features of natural product hits and that natural substances have evolved over a very long selection process to form optimal interactions with biological macromolecules, but by improvements in structure-identification, separation, and target identification. Recently, broad interest in combination screening to identify molecules that synergize with existing classes of antibacterial and antifungal drugs as an approach to improve efficacy has emerged. Our anti-fungi compound library is an effective tool for drug repurposing screening and combination screening.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L4500

Anti-Fungal Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 535 antifungal compounds effective for drug repurposing screening, combination screening and biological investigation.
  • Contains antifungal agents to treat tinea corporis and Candidiasis, and compounds inhibiting the fungal-specific targets.
  • Bioactivity and safety confirmed by clinical research and trials, some of which are FDA approved;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
  • This compound library is provided at a concentration of 10 mM in DMSO. A small number of compounds may be provided in different solvents or concentrations due to solubility or stability requirements. Please refer to the specific product information for details.

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Library Customization | TargetMol Library Composition

Antifungal
Antibacterial
Antibiotic
Apoptosis
Endogenous Metabolite
Parasite
Autophagy
Cytochromes P450
ROS
Antioxidant
Anti-infection
Influenza Virus
Reactive Oxygen Species
Antifection
DNA/RNA Synthesis
NF-κB
Interleukin
Caspase
COX
Microtubule Associated
Bcl-2 Family
p38 MAPK
Calcium Channel
Ferroptosis
MMP
TNF
Dehydrogenase
PPAR
PI3K
Akt
AChR
Virus Protease
Phosphatase
Wnt/beta-catenin
Potassium Channel
HSV
Nrf2
HIV Protease
JNK
VEGFR
Sodium Channel
mTOR
Mitochondrial Metabolism
Antiviral
HDAC
PKC
Topoisomerase
Lipoxygenase
Phospholipase
5-HT Receptor
Tyrosinase
CDK
Cholinesterase (ChE)
Ras
Estrogen Receptor/ERR
Beta Amyloid
NO Synthase
IL Receptor
STAT
AMPK
SARS-CoV
Epigenetic Reader Domain
HCV Protease
Integrin
Dopamine Receptor
MDM-2/p53
MAO
Hedgehog/Smoothened
ERK
ATPase
Glucocorticoid Receptor
JAK
FKBP
glycosidase
Histamine Receptor
HSP
GABA Receptor
Estrogen/progestogen Receptor
Carbonic Anhydrase
Proton pump
HIF/HIF Prolyl-Hydroxylase
Mitophagy
Immunology/Inflammation related
Androgen Receptor
NADPH
Glucosidase
OXPHOS
PARP
AhR
Monoamine Oxidase
PKA
ribosome
Aryl Hydrocarbon Receptor
PGK1
Adenosine Receptor
NADPH-oxidase
Nucleoside Antimetabolite/Analog
IRE1
Proteasome
Monoamine Transporter
RSV
Cannabinoid Receptor
c-Myc
CRM1
NOS
Drug Metabolite
p53
Wee1
HIF
Serine Protease
Gamma-secretase
PAFR
TRP/TRPV Channel
Free radical scavengers
Amylase
Adenosine Deaminase
Cysteine Protease
Reductase
transporter
Platelet aggregation
Src
RAAS
Retinoid Receptor
Cuproptosis
p62
Glutaminase
Monocarboxylate transporter
Advanced Glycation End Products
CaMK
NOD-like Receptor (NLR)
GSK-3
IDO
Factor Xa
EGFR
Indoleamine 2,3-Dioxygenase (IDO)
GTPase
PTEN
FAAH
DNA
Xanthine Oxidase
Epoxide Hydrolase
Amino Acids and Derivatives
E1/E2/E3 Enzyme
Arginase
IGF-1R
PERK
NOD
Sirtuin
Hydroxylase
Histone Acetyltransferase
Photosystem (PS)
Cell Cycle Arrest
NMDAR
UGT
HBV
LTR
HMG-CoA Reductase
IκB/IKK
Reverse Transcriptase
IFNAR
Aurora Kinase
MicroRNA
Fatty Acid Synthase
Myosin
Opioid Receptor
PD-1/PD-L1
ABC Transporter
ADC Cytotoxin

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