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Anti-SLC2A8 Polyclonal Antibody is a Rabbit antibody targeting SLC2A8. Anti-SLC2A8 Polyclonal Antibody can be used in WB,ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $221 | 7-10 days | |
100 μL | $372 | 7-10 days |
Description | Anti-SLC2A8 Polyclonal Antibody is a Rabbit antibody targeting SLC2A8. Anti-SLC2A8 Polyclonal Antibody can be used in WB,ELISA. |
Synonyms | solute carrier family 2(facilitated glucose transporter) member 8, GLUTX1, GLUT-8, Glucose transporter type X1, Glucose transporter type 8, Glucose Transporter 8 |
Ig Type | IgG |
Reactivity | Mouse,Rat (predicted:Human) |
Verified Activity | 1. Sample: Lane 1: Mouse Cerebrum tissue lysates Lane 2: Rat Cerebrum tissue lysates Primary: Anti-GLUT8 (TMAB-01718) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa 2. Sample: TM4 Cell (Mouse) Lysate at 40 μg Primary: Anti-GLUT8 (TMAB-01718) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 52 kDa Observed band size: 52 kD |
Application | |
Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Note=Principally intracellular. May move between intracellular vesicles and the plasma membrane. The dileucine internalization motif is critical for intracellular sequestration. Insulin induces a change in the intracellular localization and gives rise to insertion in the plasma membrane. |
Tissue Specificity | Highest level of expression in placenta and testis. Highly expressed in adult and pubertal testis, but not prepubertal testis. Lower levels of expression in brain, liver, heart, kidney, fat and skeletal muscle. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | Glucose transporter 8 is an insulin-regulated facilitative glucose transporter. It binds cytochalasin B in a glucose-inhibitable manner. It appears to be a dual-specific sugar transporter as it can be inhibited by fructose. It is highly expressed in testis, where it is down-regulated by estrogen, but not in testicular carcinoma. Lower amounts are present in most other tissues. |
Immunogen | KLH conjugated synthetic peptide: human GLUT8 |
Antigen Species | Human |
Gene Name | SLC2A8 |
Gene ID | |
Protein Name | Solute carrier family 2, facilitated glucose transporter member 8 |
Uniprot ID |
Molecular Weight | Theoretical: 52 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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