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Anti-CNDP2 Antibody (3V464) is a Rabbit antibody targeting CNDP2. Anti-CNDP2 Antibody (3V464) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-CNDP2 Antibody (3V464) is a Rabbit antibody targeting CNDP2. Anti-CNDP2 Antibody (3V464) can be used in IHC-P. |
Alias | PEPA, HsT2298, HEL-S-13, CPGL, CNDP dipeptidase 2 (metallopeptidase M20 family), CN2 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 3V464 |
Reactivity | Mouse |
Verified Activity | Immunochemical staining of mouse CNDP2 in mouse kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to nephric tubule. |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CNDP2 (rM CNDP2; TMPY-01739; NP_075638.2; Met1-Asn475). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Cytosolic non-specific dipeptidase, also known as CNDP dipeptidase 2, Glutamate carboxypeptidase-like protein 1, Peptidase A, CNDP2 and CN2, is a cytoplasm protein which belongs to thepeptidase M2A family. CNDP2 / CPGL is a cytosolic enzyme that can hydrolyze carnosine to yield l-histidine and beta-alanine. CNDP2 / CPGL hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Itmay be play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells. Isoform1 of CNDP2 / CPGL is ubiquitously expressed with higher levels in kidney and liver (at protein level). Isoform2 of CNDP2 / CPGL is expressed in fetal tissues, it is only expressed in adult liver and placental tissues. CNDP2 / CPGL is highly expressed in the histaminergic neurons in the tuberomammillary nucleus, implying that it may supply histidine to histaminergic neurons for histamine synthesis. |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse CNDP2 protein (TMPY-01739) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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