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(S,R,S)-AHPC-C6-NH2 dihydrochloride

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Catalog No. T39872Cas No. 2341796-77-6
Alias VH032-C6-NH2 dihydrochloride, (S,R,S)-AHPC-C6-NH2 dihydrochloride

(S, R, S)-AHPC-C6-NH2 dihydrochloride (also known as VH032-C6-NH2 dihydrochloride) is a synthesized compound that functions as a ligand-linker conjugate for E3 ligase. It incorporates the VH032-based VHL ligand along with a linker, which is used for the degradation of AKT PROTAC.

(S,R,S)-AHPC-C6-NH2 dihydrochloride
Other Forms of (S,R,S)-AHPC-C6-NH2 dihydrochloride:

(S,R,S)-AHPC-C6-NH2 dihydrochloride

😃Good
Catalog No. T39872Alias VH032-C6-NH2 dihydrochloride, (S,R,S)-AHPC-C6-NH2 dihydrochlorideCas No. 2341796-77-6
(S, R, S)-AHPC-C6-NH2 dihydrochloride (also known as VH032-C6-NH2 dihydrochloride) is a synthesized compound that functions as a ligand-linker conjugate for E3 ligase. It incorporates the VH032-based VHL ligand along with a linker, which is used for the degradation of AKT PROTAC.
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Product Introduction

Bioactivity
Description
(S, R, S)-AHPC-C6-NH2 dihydrochloride (also known as VH032-C6-NH2 dihydrochloride) is a synthesized compound that functions as a ligand-linker conjugate for E3 ligase. It incorporates the VH032-based VHL ligand along with a linker, which is used for the degradation of AKT PROTAC.
In vitro
PROTACs consist of two distinct ligands linked together: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
SynonymsVH032-C6-NH2 dihydrochloride, (S,R,S)-AHPC-C6-NH2 dihydrochloride
Chemical Properties
Molecular Weight594.21
FormulaC29H44ClN5O4S
Cas No.2341796-77-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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Keywords

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