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Anti-Tetranectin Antibody (2C970) is a Rabbit antibody targeting Tetranectin. Anti-Tetranectin Antibody (2C970) can be used in IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-Tetranectin Antibody (2C970) is a Rabbit antibody targeting Tetranectin. Anti-Tetranectin Antibody (2C970) can be used in IHC-P. |
Alias | Tna, C-type lectin domain family 3, member B |
Ig Type | Monoclonal Rabbit IgG |
Clone | 2C970 |
Reactivity | Human |
Verified Activity | 1. Immunochemical staining of human CLEC3B in human squamous cell carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CLEC3B in human kidney with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections). |
Application | IHC-P |
Recommended Dose | IHC-P: 1:100-1:500 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human Tetranectin / CLEC3B (rh Tetranectin / CLEC3B; TMPY-02140; AAX37102.1; Met1-Val202). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Tetranectin (TN), also known as C-type lectin domain family 3, member B (CLEC3B) is a member of the C-type lectin Family. It is plasminogen kringle 4 binding protein and regulates fibrinolysis and proteolytic processes via binding to plasminogen. Tetranectin has been suggested to play a role in tissue remodeling, due to its ability to stimulate plasminogen activation and its expression in developing tissues such as developing bone and muscle. Tetranectin enhances plasminogen activation by a tissue-type plasminogen activator so that it has been suggested to play a role in tissue remodeling. Tetranectin may play a role in the wound healing process. Tetranectin may play a role in neurological diseases and may serve as a diagnostic aid in multiple sclerosis (MS). Tetranectin was found significantly under-expressed in both serum and saliva of metastatic oral squamous cell carcinoma (OSCC) compared to primary OSCC. Tetranectin is thought to enhance proteolytic processes enabling tumor cells to invade and metastasize. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Tetranectin / CLEC3B protein (TMPY-02140) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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