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Azido-PEG10-alcohol

Name: Azido-PEG10-alcohol
Brand: TargetMol
SKU: T14413
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T14413Cas No. 877239-09-3

Azido-PEG10-alcohol, a PEG-based PROTAC linker, is utilized in PROTAC synthesis [1].

Azido-PEG10-alcohol

🥰Excellent

Catalog No. T14413Cas No. 877239-09-3

Azido-PEG10-alcohol, a PEG-based PROTAC linker, is utilized in PROTAC synthesis [1].

Pack Size	Price	Availability	Quantity
25 mg	$29	In Stock

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Batch Information

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Purity:≥98%

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COA HNMR

Product Introduction

Bioactivity

Description	Azido-PEG10-alcohol, a PEG-based PROTAC linker, is utilized in PROTAC synthesis [1].
In vitro	PROTACs consist of two distinct ligands linked by a connector: one ligand binds to an E3 ubiquitin ligase, while the other binds to the target protein. PROTACs utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

Chemical Properties

Molecular Weight	483.55
Formula	C₂₀H₄₁N₃O₁₀
Cas No.	877239-09-3
Smiles	C(COCCOCCOCCOCCN=[N+]=[N-])OCCOCCOCCOCCOCCO
Relative Density.	no data available

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 10 mM, Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0680 mL	10.3402 mL	20.6804 mL	103.4019 mL
5 mM	0.4136 mL	2.0680 mL	4.1361 mL	20.6804 mL
10 mM	0.2068 mL	1.0340 mL	2.0680 mL	10.3402 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc