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CLEC10A Protein, Human, Recombinant (hFc)

Catalog No. TMPY-02971
Synonyms: HML2, CD301, CLECSF13, HML, MGL, C-type lectin domain family 10, member A, CLECSF14

CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
CLEC10A Protein, Human, Recombinant (hFc)
Pack Size Availability Price/USD Quantity
50 μg In stock $ 258.00
100 μg 5 days $ 440.00
200 μg 5 days $ 753.00
500 μg 5 days $ 1,530.00
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Biological Description
Technical Params
Product Properties
References and Literature
Biological Information Testing in progress
Description CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
Species Human
Expression System HEK293 Cells
Tag N-hFc
Accession Number Q8IUN9-2
Synonyms HML2, CD301, CLECSF13, HML, MGL, C-type lectin domain family 10, member A, CLECSF14
Construction The Human CLEC10A (Q8IUN9-2) (Gln61-His292) was expressed, with the fused Fc region of Human IgG1 at the N-terminus.
Protein Purity > 85 % as determined by SDS-PAGE

Molecular Weight 54.6 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is a type II transmembrane glycoproteins and is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). There are 2 homologues: MGL1 and MGL2 (CD301a and CD301b) in mice. MGL1/CD301a induces both the production and secretion of interleukin (IL)-10. MGL1/CD301a plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.

References and Literature

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Keywords

CLEC10A Protein, Human, Recombinant (hFc) HML-2 HML2 CLECSF 13 CD301 CD-301 CLECSF13 CLECSF-14 HML MGL CLECSF-13 HML 2 C-type lectin domain family 10, member A CLECSF 14 CD 301 CLECSF14 recombinant recombinant-proteins proteins protein

 

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