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Anti-DPP2 Antibody-HRP (7R25) is a HRP-conjugated Mouse antibody targeting DPP2. Anti-DPP2 Antibody-HRP (7R25) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $294 | 7-10 days |
Description | Anti-DPP2 Antibody-HRP (7R25) is a HRP-conjugated Mouse antibody targeting DPP2. Anti-DPP2 Antibody-HRP (7R25) can be used in ELISA. |
Alias | QPP, DPPII, Dpp2, dipeptidyl-peptidase 7 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 7R25 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 0.1-1 μg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human DPPII / DPP7 (rhDPPII; TMPY-00777; NP_037511.2; Met 1-Leu 492). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | DPP7 (dipeptidylpeptidase 7), also known as DPPII and DPP2, is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. Dipeptidyl peptidases (DPPs) have post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. DPPs mediate regulatory activity of their substrates and have been linked to a variety of diseases including type 2 diabetes, obesity and cancer. DPPs can bind specific voltage-gated potassium channels and alter their expression and biophysical properties and may also influence T cells. DPP proteins include DPRP1, DPRP2, DPP3, DPP7, DPP10, DPPX and CD26. It localizes to lysosomes. DPP7 localizes to lysosomes and exists as a homodimer via its leucine zipper motif and is involved in the degradation of oligopeptides. In response to calcium release, it can be secreted in its active form. It is essential for lymphocyte survival, as the inhibition of DPP7 results in quiescent cell apoptosis. |
Conjucates | HRP |
Others Formats | Unconjugated |
Antibody Types Available | 2 |
Immunogen | Human cell-derived DPPII protein (TMPY-00777) |
Antigen Species | Human |
Biology Area | Serine Proteases and Regulators |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
Transport | Shipping with blue ice. |
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