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Anti-Beta subunit Cholera Toxin Polyclonal Antibody
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Catalog No. TMAB-00212
Alias β subunit Cholera Toxin, VC1456, TOXB, TOX B, CTXB, CTX B, CHTB_VIBCH, Choleragenoid, Cholera Toxin beta, Cholera toxin B protein, Cholera enterotoxin subunit B, Cholera enterotoxin gamma chain, Cholera enterotoxin beta chain, Cholera enterotoxin B chain, beta subunit Cholera Toxin
Anti-Beta subunit Cholera Toxin Polyclonal Antibody is a Rabbit antibody targeting Beta subunit Cholera Toxin. Anti-Beta subunit Cholera Toxin Polyclonal Antibody can be used in ELISA,WB.
Anti-Beta subunit Cholera Toxin Polyclonal Antibody
Anti-Beta subunit Cholera Toxin Polyclonal Antibody
😃Good
Catalog No. TMAB-00212Alias β subunit Cholera Toxin, VC1456, TOXB, TOX B, CTXB, CTX B, CHTB_VIBCH, Choleragenoid, Cholera Toxin beta, Cholera toxin B protein, Cholera enterotoxin subunit B, Cholera enterotoxin gamma chain, Cholera enterotoxin beta chain, Cholera enterotoxin B chain, beta subunit Cholera Toxin
Anti-Beta subunit Cholera Toxin Polyclonal Antibody is a Rabbit antibody targeting Beta subunit Cholera Toxin. Anti-Beta subunit Cholera Toxin Polyclonal Antibody can be used in ELISA,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $220 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Beta subunit Cholera Toxin Polyclonal Antibody is a Rabbit antibody targeting Beta subunit Cholera Toxin. Anti-Beta subunit Cholera Toxin Polyclonal Antibody can be used in ELISA,WB. |
| Synonyms | β subunit Cholera Toxin, VC1456, TOXB, TOX B, CTXB, CTX B, CHTB_VIBCH, Choleragenoid, Cholera Toxin beta, Cholera toxin B protein, Cholera enterotoxin subunit B, Cholera enterotoxin gamma chain, Cholera enterotoxin beta chain, Cholera enterotoxin B chain, beta subunit Cholera Toxin |
| Ig Type | IgG |
| Reactivity | (predicted:Cholera Toxin) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. Host cell membrane (Potential). |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP. |
| Immunogen | KLH conjugated synthetic peptide: CTXB/beta subunit Cholera Toxin |
| Gene Name | ctxB |
| Protein Name | Cholera enterotoxin subunit B |
| Biology Area | Cholera Toxin |
| Function | The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself. |
| Molecular Weight | Theoretical: 12 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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