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Anti-IL-18R alpha Antibody (2O292)

😃Good
Catalog No. TMAY-01643
Alias interleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a

Anti-IL-18R alpha Antibody (2O292) is a Mouse antibody targeting IL-18R alpha. Anti-IL-18R alpha Antibody (2O292) can be used in ELISA(Det).

Anti-IL-18R alpha Antibody (2O292)

Anti-IL-18R alpha Antibody (2O292)

😃Good
Catalog No. TMAY-01643Alias interleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a
Anti-IL-18R alpha Antibody (2O292) is a Mouse antibody targeting IL-18R alpha. Anti-IL-18R alpha Antibody (2O292) can be used in ELISA(Det).
Pack SizePriceAvailabilityQuantity
20 μL$68 7-10 days
100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-IL-18R alpha Antibody (2O292) is a Mouse antibody targeting IL-18R alpha. Anti-IL-18R alpha Antibody (2O292) can be used in ELISA(Det).
Aliasinterleukin 18 receptor 1, IL-1Rrp, IL1RRP, IL18RA, CDw218a, CD218a
Ig Type
Monoclonal Mouse IgG1
Clone
2O292
Reactivity
Human
Application
ELISA(Det)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL18R1 (rh IL18R1; TMPY-01219; NP_003846.1; Met1-Arg329). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
Research BackgroundInterleukin-18 receptor 1 (IL18R1) also known as CD218 antigen-like family member A, CDw218a, IL1 receptor-related protein, and CD218a, is an interleukin receptor of the immunoglobulin superfamily. IL18R1 is found expressed in the lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta, and heart, and is absent from the brain, skeletal muscle, pancreas, and kidney. A high level of expression is found in Hodgkin disease cell lines. This receptor is specifically bound to interleukin 18 (IL18) and is essential for IL18 mediated signal transduction. IL18R1 contains 3 Ig-like C2-type (immunoglobulin-like) domains and 1 TIR domain. It is a single-pass type I membrane protein. IFN-alpha and IL12 are reported to induce the expression of this receptor in NK and T cells. The increased expression of IL18R1 may contribute pathogenically to disease and is therefore a potential therapeutic target. The absence of a genetic association in the IL18R1 gene itself suggests regulation from other parts of the genome, or as part of the inflammatory cascade in multiple sclerosis without a prime genetic cause.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
HRP
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human IL18R1 Protein (TMPY-01219)
Antigen Species
Human
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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