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Anti-S6K1/RPS6KB1 Antibody (6S46)
😃Good
Catalog No. TMAY-00251
Alias STK14A, S6K-β-1, S6K-beta-1, S6K1, S6K, RPS6KB1, ribosomal protein S6 kinase, polypeptide 1, PS6K, p70-α, p70-S6K, p70-alpha, p70(S6K)-α, p70(S6K)-alpha, p70 S6KA
Anti-S6K1/RPS6KB1 Antibody (6S46) is a Mouse antibody targeting S6K1/RPS6KB1. Anti-S6K1/RPS6KB1 Antibody (6S46) can be used in ELISA.
Anti-S6K1/RPS6KB1 Antibody (6S46)
Anti-S6K1/RPS6KB1 Antibody (6S46)
😃Good
Catalog No. TMAY-00251Alias STK14A, S6K-β-1, S6K-beta-1, S6K1, S6K, RPS6KB1, ribosomal protein S6 kinase, polypeptide 1, PS6K, p70-α, p70-S6K, p70-alpha, p70(S6K)-α, p70(S6K)-alpha, p70 S6KA
Anti-S6K1/RPS6KB1 Antibody (6S46) is a Mouse antibody targeting S6K1/RPS6KB1. Anti-S6K1/RPS6KB1 Antibody (6S46) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | STK14A, S6K-β-1, S6K-beta-1, S6K1, S6K, RPS6KB1, ribosomal protein S6 kinase, polypeptide 1, PS6K, p70-α, p70-S6K, p70-alpha, p70(S6K)-α, p70(S6K)-alpha, p70 S6KA |
| Ig Type | Mouse IgG2a |
| Clone | 6S46 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PS6K / RPS6KB1 (rh PS6K / RPS6KB1; TMPY-04540; P23443; Met1-Leu525). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | PS6K, also known as RPS6KB1, is a serine/threonine-protein kinase. It belongs to the RSK (ribosomal s6 kinase) family. Members of this family function in signal transduction. PS6K is an isoform of p70 ribosomal S6 kinase (S6K). S6K can be activated by mitogenic stimuli such as growth factors, insulin and cytokines. It phosphorylates the ribosomal protein S6. PS6K also phosphorylates other proteins such as elF4B, eEF2K and SKAR. It is a crucial effector of mTOR(rapamycin) signaling. PS6K is dissociated from the EIF3 complex and activated upon mitogenic stimulation, phosphorylation by the mammalian target of mTOR complex 1 (mTORC1). Its active form then phosphorylates and activates several substrates in the preinitiation complex, including the EIF2B complex and the cap-binding complex component EIF4B. PS6K also functions in cell proliferation, cell growth and cell cycle progression. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human PS6K / RPS6KB1 protein (TMPY-04540) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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