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Anti-Phospho-AKT1 (Tyr326) Polyclonal Antibody

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Catalog No. TMAC-00111

Anti-Phospho-AKT1 (Tyr326) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Tyr326). Anti-Phospho-AKT1 (Tyr326) Polyclonal Antibody can be used in WB.

Anti-Phospho-AKT1 (Tyr326) Polyclonal Antibody

Anti-Phospho-AKT1 (Tyr326) Polyclonal Antibody

😃Good
Catalog No. TMAC-00111
Anti-Phospho-AKT1 (Tyr326) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Tyr326). Anti-Phospho-AKT1 (Tyr326) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3167-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-AKT1 (Tyr326) Polyclonal Antibody is a Rabbit antibody targeting Phospho-AKT1 (Tyr326). Anti-Phospho-AKT1 (Tyr326) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-3000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundAKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface. Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the attenuation of insulin signaling.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of tyrosine 326 (N-D-Y(p)-G-R) derived from Human Akt
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 60 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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