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7α-(Thiomethyl)spironolactone

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Catalog No. T37362Cas No. 38753-77-4
Alias 7α-Thiomethylspironolactone

7α-(Thiomethyl)spironolactone is a nuclear steroid receptor antagonist and a major metabolite of the synthetic steroid spironolactone. 7α-(Thiomethyl)spironolactone is used in pharmacological studies, including research on steroid metabolism, nuclear receptor signaling, and coronavirus-related investigations.

7α-(Thiomethyl)spironolactone

7α-(Thiomethyl)spironolactone

🥰Excellent
Catalog No. T37362Alias 7α-ThiomethylspironolactoneCas No. 38753-77-4
7α-(Thiomethyl)spironolactone is a nuclear steroid receptor antagonist and a major metabolite of the synthetic steroid spironolactone. 7α-(Thiomethyl)spironolactone is used in pharmacological studies, including research on steroid metabolism, nuclear receptor signaling, and coronavirus-related investigations.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$243-In Stock
5 mg$737-In Stock
10 mgPreferential-In Stock
25 mgPreferential-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:>99.99%
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Product Introduction

Bioactivity
Description
7α-(Thiomethyl)spironolactone is a nuclear steroid receptor antagonist and a major metabolite of the synthetic steroid spironolactone. 7α-(Thiomethyl)spironolactone is used in pharmacological studies, including research on steroid metabolism, nuclear receptor signaling, and coronavirus-related investigations.
Synonyms7α-Thiomethylspironolactone
Chemical Properties
Molecular Weight388.56
FormulaC23H32O3S
Cas No.38753-77-4
SmilesC[C@@]12[C@]3(CC[C@]1([C@]4([C@](CC2)([C@]5(C)C(C[C@H]4SC)=CC(=O)CC5)[H])[H])[H])OC(=O)CC3
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (205.89 mM), Sonication is recommended.
Chloroform: Slightly soluble
Ethyl Acetate: Slightly soluble
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5736 mL12.8680 mL25.7361 mL128.6803 mL
5 mM0.5147 mL2.5736 mL5.1472 mL25.7361 mL
10 mM0.2574 mL1.2868 mL2.5736 mL12.8680 mL
20 mM0.1287 mL0.6434 mL1.2868 mL6.4340 mL
50 mM0.0515 mL0.2574 mL0.5147 mL2.5736 mL
100 mM0.0257 mL0.1287 mL0.2574 mL1.2868 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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