Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GPR81 agonist 1 is a potent and selective GPR81 agonist with high affinity for human and mouse GPR81.GPR81 agonist 1 inhibits lipolysis of differentiated 3T3-L1 adipocytes, improves insulin sensitivity and glycaemic control in mouse models of insulin resistance and diabetes, and can be used in the study of diabetes and obesity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 153.00 | |
5 mg | In stock | $ 377.00 | |
10 mg | In stock | $ 622.00 | |
25 mg | In stock | $ 1,080.00 | |
50 mg | In stock | $ 1,610.00 | |
100 mg | In stock | $ 2,390.00 |
Description | GPR81 agonist 1 is a potent and selective GPR81 agonist with high affinity for human and mouse GPR81.GPR81 agonist 1 inhibits lipolysis of differentiated 3T3-L1 adipocytes, improves insulin sensitivity and glycaemic control in mouse models of insulin resistance and diabetes, and can be used in the study of diabetes and obesity. |
In vitro | GPR81 agonist 1 (1-1000 nM) inhibits fat breakdown in differentiated 3T3-L1 adipocytes[1]. |
In vivo | GPR81 agonist 1, when administered intraperitoneally at a dose of 100 mg/kg, inhibits fat breakdown in mice without causing skin flushing and exhibits good bioavailability[1]. |
Molecular Weight | 446.63 |
Formula | C22H30N4O2S2 |
CAS No. | 1620992-67-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL(67.17 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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GPR81 agonist 1 1620992-67-7 Endocrinology/Hormones GPCR/G Protein GPR inhibitor inhibit