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RNASE3 Protein, Human, Recombinant (His)

(Synonyms: RNS3, RNASE3, RNase 3, Ribonuclease 3, Eosinophil Cationic Protein, ECP) Copy Product Info

Synonyms: RNS3, RNASE3, RNase 3, Ribonuclease 3, Eosinophil Cationic Protein, ECP

Catalog No. TMPJ-00574 Copy Product Info
Purity: 96%
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
RNASE3 Protein, Human, Recombinant (His)
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Pack SizePriceUSA StockGlobal StockQuantity
10 µg$1837-10 days7-10 days
20 µg$2927-10 days7-10 days
50 µg$5457-10 days7-10 days
100 µg$7927-10 days7-10 days
200 µg$1,1507-10 days7-10 days
500 µg$1,9007-10 days7-10 days
1 mg$2,7307-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:96%
Color:Transparent
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Species
Human
Expression System
HEK293 Cells
TagC-6xHis
Accession NumberAAH96060.1
Amino AcidArg28-Ile160
ConstructionArg28-Ile160
Protein Purity
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
RNASE3 Protein, Human, Recombinant (His)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationSupplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 1 mMDTT, 10% Glycerol, pH 7.5.
SynonymsRNS3, RNASE3, RNase 3, Ribonuclease 3, Eosinophil Cationic Protein, ECP
Research Background
Ribonuclease 3 (RNASE3) is a basic protein that is localized to the eosinophil primary matrix and belongs to the pancreatic ribonuclease family. RNASE3 is released during degranulation of eosinophils. RNASE3 possesses a wide variety of biological activities. RNASE3 interacts with bacterial lipopolysaccharide (LPS) and lipoteichoic acid (LTA). RNASE3 exhibits antibacterial activity, including cytoplasmic membrane depolarization of preferentially Gram-negative, but also Gram-positive strains. It promotes E. coli outer membrane detachment, alteration of the overall cell shape and partial loss of cell content.
Chemical Properties
Molecular Weight25-35 KDa (reducing condition)
Storage & Solubility Information
ShippingProteins are shipped with blue ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: RNASE3 Protein, Human, Recombinant (His) chemical structure | RNASE3 Protein, Human, Recombinant (His) molecular weight