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Macropa-NH2 hydrochloride

Name: Macropa-NH2 hydrochloride
Brand: TargetMol
SKU: T11938
Price: 163 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T11938Cas No. 2443966-86-5

Macropa-NH2 hydrochloride is a ligand with nickel coordination activity that forms stable complexes with metals.

Macropa-NH2 hydrochloride

🥰Excellent

Purity: 98.84%

Catalog No. T11938Cas No. 2443966-86-5

Macropa-NH2 hydrochloride is a ligand with nickel coordination activity that forms stable complexes with metals.

Pack Size	Price	Availability
1 mg	$163	In Stock
5 mg	$413	In Stock
10 mg	$689	In Stock
25 mg	$1,450	In Stock
50 mg	$2,360	In Stock
1 mL x 10 mM (in DMSO)	$529	In Stock

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Bulk & Custom

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:98.84%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Macropa-NH2 hydrochloride is a ligand with nickel coordination activity that forms stable complexes with metals.
In vitro	Macropa-NH2 hydrochloride, as a precursor of Macropa-NCS, is a promising therapeutic radiopharmaceutical that can be used for the treatment of soft tissue metastases[1].

Chemical Properties

Molecular Weight	584.06
Formula	C₂₆H₃₈ClN₅O₈
Cas No.	2443966-86-5
Smiles	Cl.Nc1cc(CN2CCOCCOCCN(Cc3cccc(n3)C(O)=O)CCOCCOCC2)nc(c1)C(O)=O
Relative Density.	no data available

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 80 mg/mL (136.97 mM), Sonication is recommended.

DMSO: 83.33 mg/mL (142.67 mM), Sonication is recommended.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7122 mL	8.5608 mL	17.1215 mL	85.6076 mL
5 mM	0.3424 mL	1.7122 mL	3.4243 mL	17.1215 mL
10 mM	0.1712 mL	0.8561 mL	1.7122 mL	8.5608 mL
20 mM	0.0856 mL	0.4280 mL	0.8561 mL	4.2804 mL
50 mM	0.0342 mL	0.1712 mL	0.3424 mL	1.7122 mL
100 mM	0.0171 mL	0.0856 mL	0.1712 mL	0.8561 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc