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TCO-PEG4-NHS ester

Name: TCO-PEG4-NHS ester
Brand: TargetMol
SKU: T17017
Price: 61 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T17017Cas No. 1613439-69-2

TCO-PEG4-NHS ester is a PROTAC linker bridge in the PEG class, used for synthesizing various PROTAC molecules. As a cleavable and synthetic ADC, it is also utilized in the synthesis of antibody-drug conjugates (ADCs).

TCO-PEG4-NHS ester

🥰Excellent

Purity: 99.75%

Catalog No. T17017Cas No. 1613439-69-2

Pack Size	Price	Availability
5 mg	$61	In Stock
10 mg	$97	In Stock
25 mg	$197	In Stock
50 mg	$313	In Stock
100 mg	$493	In Stock

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Batch Information

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Purity:99.75%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	514.57
Formula	C₂₄H₃₈N₂O₁₀
Cas No.	1613439-69-2
Smiles	O(C(CCOCCOCCOCCOCCNC(OC1CCCC=CCC1)=O)=O)N2C(=O)CCC2=O
Relative Density.	1.23 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 25.73 mg/mL (50 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9434 mL	9.7169 mL	19.4337 mL	97.1685 mL
5 mM	0.3887 mL	1.9434 mL	3.8867 mL	19.4337 mL
10 mM	0.1943 mL	0.9717 mL	1.9434 mL	9.7169 mL
20 mM	0.0972 mL	0.4858 mL	0.9717 mL	4.8584 mL
50 mM	0.0389 mL	0.1943 mL	0.3887 mL	1.9434 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc