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Anti-CES3/Carboxylesterase 3 Antibody (9D803)
🥰Excellent
Catalog No. TMAY-01668
Anti-CES3/Carboxylesterase 3 Antibody (9D803) is a Rabbit antibody targeting CES3/Carboxylesterase 3. Anti-CES3/Carboxylesterase 3 Antibody (9D803) can be used in IHC-P.
Anti-CES3/Carboxylesterase 3 Antibody (9D803)
Anti-CES3/Carboxylesterase 3 Antibody (9D803)
🥰Excellent
Catalog No. TMAY-01668
Anti-CES3/Carboxylesterase 3 Antibody (9D803) is a Rabbit antibody targeting CES3/Carboxylesterase 3. Anti-CES3/Carboxylesterase 3 Antibody (9D803) can be used in IHC-P.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CES3/Carboxylesterase 3 Antibody (9D803) is a Rabbit antibody targeting CES3/Carboxylesterase 3. Anti-CES3/Carboxylesterase 3 Antibody (9D803) can be used in IHC-P. |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9D803 |
| Reactivity | Human |
| Verified Activity | 1. Immunochemical staining of human CES3 in human liver with rabbit monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). 2. Immunochemical staining of human CES3 in human colon with rabbit monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections). |
| Application | IHC-P |
| Recommended Dose | IHC-P: 1:500-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CES3 / Carboxylesterase 3 (rh CES3 / Carboxylesterase 3; NP_079198.2Met1-Glu561). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Carboxylesterases hydrolyze esters of short-chain fatty acids and have roles in animals ranging from signal transduction to xenobiotic detoxification. In enzymology, a carboxylesterase is an enzyme that catalyzes the chemical reaction: a carboxylic ester + H2O = an alcohol + a carboxylate. Most enzymes from this group belong to the superfamily of hydrolases with alpha/beta protein fold (so called Alpha/beta hydrolase fold), specifically those acting on carboxylic ester bonds. The carboxylesterase family of evolutionarily related proteins (those with clear sequence homology to each other) includes a number of proteins with different substrate specificities, such as acetylcholinesterases. Carboxylesterase 3, also known as Liver carboxylesterase 31 homolog and CES3, is a endoplasmic reticulum lumen which belongs to thetype-B carboxylesterase/lipase family. CES3 is involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. CES3 shows low catalytic efficiency for hydrolysis of CPT-11, a prodrug for camptothecin used in cancer therapeutics. CES3 is expressed in liver, colon and small intestine. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human CES3 / Carboxylesterase 3 Protein |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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