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N-Decanoyl cyclopentylamide

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Catalog No. T88122Cas No. 540796-75-6
Alias C10-CPA

N-Decanoyl cyclopentylamide (C10-CPA) serves as a potent quorum sensing inhibitor in Pseudomonas aeruginosa, disrupting the expression of virulence factors governed by both the las and rhl systems. It effectively suppresses the production of elastase, pyocyanin, rhamnolipid, and hinders biofilm formation.

N-Decanoyl cyclopentylamide

N-Decanoyl cyclopentylamide

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Catalog No. T88122Alias C10-CPACas No. 540796-75-6
N-Decanoyl cyclopentylamide (C10-CPA) serves as a potent quorum sensing inhibitor in Pseudomonas aeruginosa, disrupting the expression of virulence factors governed by both the las and rhl systems. It effectively suppresses the production of elastase, pyocyanin, rhamnolipid, and hinders biofilm formation.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$1,5202-4 weeks2-4 weeks
50 mg$1,9802-4 weeks2-4 weeks
100 mg$2,5002-4 weeks2-4 weeks
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
N-Decanoyl cyclopentylamide (C10-CPA) serves as a potent quorum sensing inhibitor in Pseudomonas aeruginosa, disrupting the expression of virulence factors governed by both the las and rhl systems. It effectively suppresses the production of elastase, pyocyanin, rhamnolipid, and hinders biofilm formation.
In vitro
N-Decanoyl cyclopentylamide (C10-CPA) inhibits quorum sensing in Pseudomonas aeruginosa, with half-maximal inhibitory concentrations for lasB-lacZ and rhlA-lacZ expression at 80 μM and 90 μM, respectively [1]. It also suppresses the production of virulence factors such as elastase, pyocyanin, rhamnolipids, and biofilm formation without affecting the growth of Pseudomonas aeruginosa PAO1 [1]. N-Decanoyl cyclopentylamide interferes with the las and rhl quorum sensing systems by disrupting the interaction between their response regulators (LasR and RhlR) and autoinducers [1].
SynonymsC10-CPA
Chemical Properties
Molecular Weight239.40
FormulaC15H29NO
Cas No.540796-75-6
SmilesO=C(NC1CCCC1)CCCCCCCCC
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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