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BSSP-4 Protein, Human, Recombinant (His)
(Synonyms: Tryptase ε, Tryptase Epsilon, Serine Protease 26, Serine Protease 22, PRSS26, PRSS22, BSSP-4, BSSP4, Brain-Specific Serine Protease 4) Copy Product InfoSynonyms: Tryptase ε, Tryptase Epsilon, Serine Protease 26, Serine Protease 22, PRSS26, PRSS22, BSSP-4, BSSP4, Brain-Specific Serine Protease 4
Catalog No. TMPJ-01320 Copy Product Info
Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after arginine and lysine residues. However, BSSP-4 is less susceptible to inhibition by common trypsin inhibitors such as aprotinin, α1-antitrypsin and secretory leukocyte protease inhibitor. BSSP-4 efficiently converts pro-urokinase- type plasminogen activator to its mature, active form.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 μg | $112 | - | In Stock | |
| 10 μg | $183 | - | In Stock | |
| 20 μg | $292 | - | In Stock | |
| 50 μg | $545 | - | In Stock | |
| 100 μg | $792 | - | In Stock | |
| 200 μg | $1,150 | 7-10 days | 7-10 days | |
| 500 μg | $1,900 | 7-10 days | 7-10 days | |
| 1 mg | $2,730 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:Greater than 95% as determined by reducing SDS-PAGE.
Color:Transparent
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after arginine and lysine residues. However, BSSP-4 is less susceptible to inhibition by common trypsin inhibitors such as aprotinin, α1-antitrypsin and secretory leukocyte protease inhibitor. BSSP-4 efficiently converts pro-urokinase- type plasminogen activator to its mature, active form. |
| Species | Human |
| Expression System | HEK293 Cells |
| Tag | C-6xHis |
| Accession Number | Q9GZN4 |
| Amino Acid | Ala33-Ser317 |
| Construction | Ala33-Ser317 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, 10% Glycerol, pH 4.5. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | Proteins are shipped with blue ice. |
| Synonyms | Tryptase ε, Tryptase Epsilon, Serine Protease 26, Serine Protease 22, PRSS26, PRSS22, BSSP-4, BSSP4, Brain-Specific Serine Protease 4 |
| Research Background |
| Molecular Weight | 33-35 KDa (reducing condition) |
| Storage | Store at low temperature Lyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: BSSP-4 Protein, Human, Recombinant (His) chemical structure | BSSP-4 Protein, Human, Recombinant (His) molecular weight
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