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4-Hydroxymethylpyrazole is the main primary metabolite of formomizole formed in the process of liver oxidation. The plasma level increases with the increase of dosage of formomizole, but the half-life is relatively short. 4-Hydroxymethylpyrazole has a certain inhibitory effect on alcohol dehydrogenase (ADH) in humans and monkeys, but its inhibitory effect is obviously lower than that of Fomepizole.


| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 200 mg | $37 | - | In Stock | |
| 500 mg | $58 | - | In Stock | |
| 1 g | $83 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $30 | - | In Stock |
| Description | 4-Hydroxymethylpyrazole is the main primary metabolite of formomizole formed in the process of liver oxidation. The plasma level increases with the increase of dosage of formomizole, but the half-life is relatively short. 4-Hydroxymethylpyrazole has a certain inhibitory effect on alcohol dehydrogenase (ADH) in humans and monkeys, but its inhibitory effect is obviously lower than that of Fomepizole. |
| Molecular Weight | 98.11 |
| Formula | C4H6N2O |
| Cas No. | 25222-43-9 |
| Smiles | OCC1=CNN=C1 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 100.00 mg/mL (1019.26 mM), Sonication is recommended. H2O: 100.00 mg/mL (1019.26 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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