SLAMF5 Protein, Human, Recombinant (His)

Name: SLAMF5 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-00229
Rating: 4.5 (1 reviews)

(Synonyms: SLAMF5, SLAM family member 5, Signaling lymphocytic activation molecule 5, Leukocyte differentiation antigen CD84, Hly9-β, Hly9-beta, Cell surface antigen MAX.3, CD84) Copy Product Info

Synonyms: SLAMF5, SLAM family member 5, Signaling lymphocytic activation molecule 5, Leukocyte differentiation antigen CD84, Hly9-β, Hly9-beta, Cell surface antigen MAX.3, CD84

Catalog No. TMPJ-00229 Copy Product Info

SLAMF5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-43 KDa and the accession number is Q9UIB8.

Pack Size	Price	USA Stock	Global Stock
5 µg	$68	7-10 days	7-10 days
10 µg	$110	7-10 days	7-10 days
20 µg	$169	7-10 days	7-10 days
50 µg	$310	7-10 days	7-10 days
100 µg	$485	7-10 days	7-10 days
200 µg	$762	7-10 days	7-10 days
500 µg	$1,390	7-10 days	7-10 days
1 mg	$1,980	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	SLAMF5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-43 KDa and the accession number is Q9UIB8.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	Q9UIB8
Amino Acid	Lys22-Arg220
Construction	Lys22-Arg220
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	SLAMF5, SLAM family member 5, Signaling lymphocytic activation molecule 5, Leukocyte differentiation antigen CD84, Hly9-β, Hly9-beta, Cell surface antigen MAX.3, CD84
Research Background	SLAM family member 5 (SLAMF5/CD84) is a type I transmembrane protein in the SLAM subgroup of the CD2 family. SLAM family proteins regulate multiple aspects of immune system function. Mature human CD84 consists of a 204 amino acid (aa) extracellular domain (ECD) with two Iglike domains,a 21 aa transmembrane segment, and a 99 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs (ITSMs). CD84 exhibits homophilic binding which is mediated by the N-terminal Ig-like domain. Ligation induces tyrosine phosphorylation in the cytoplasmic ITSMs which then recruit the signaling adaptor molecules SAP (SLAM-associated protein) and EAT-2(EWS/Fli1-activated transcript 2).CD84 signaling inhibits Fc epsilon RI-induced mast cell activation but enhances platelet activation. LPS-induced macrophage activation,T cell proliferation and IFN-γproduction, and the interactions between T cells and B cells that are required for germinal center formation.

Chemical Properties

Molecular Weight

35-43 KDa (reducing condition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.