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Anti-HEV ORF3 Polyclonal Antibody is a Rabbit antibody targeting HEV ORF3. Anti-HEV ORF3 Polyclonal Antibody can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
| Description | Anti-HEV ORF3 Polyclonal Antibody is a Rabbit antibody targeting HEV ORF3. Anti-HEV ORF3 Polyclonal Antibody can be used in ELISA. |
| Synonyms | Protein ORF3, pORF3, ORF3_HEVHY., ORF3 [Hepatitis E virus], Hepatitis E Virus ORF3 |
| Ig Type | IgG |
| Reactivity | (predicted:HEV) |
| Application | |
| Recommended Dose | ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Virion (Probable). Host cytoplasm. Host cell surface. Note=Initially cotranslationally translocated into the ER from where it is retrotranslocated to the cytoplasm. A fraction is also observed on the cell surface. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | The Hepatitis E virus is the causative agent of Hepatitis E. Its taxonomic name is Orthohepevirus A. The viral genome a single-strand of positive-sense RNA that is approximately 7200 bases in length. It encodes 3 proteins (O1, O2, O3), two of which are polyproteins, that is, they are cleaved into fragments which carry out the actual functions of the virus. The O1 protein consists of 7 such fragments, namely Met (Methyltransferase), Y (Y-domain), Plp (Papain like protease), V (proline-rich variable region), X (X-domain, macro-domain), Hel (Helicase), and Rdrp (RNA dependent RNA polymerase). The Pvx domain is a fusion protein consisting of the Plp, V and X domains. The O3 protein is encoded by a single open reading frame (ORF3). The O2 protein encodes the capsid, which is composed of 3 domains, namely the shell domain (S) and two protruding domains (P1, P2). Numbers in the figure indicate positions in the RNA sequence. |
| Immunogen | KLH conjugated synthetic peptide: HEV ORF3 |
| Gene Name | ORF3 |
| Protein Name | Protein ORF3 |
| Biology Area | Hepatitis A/C/E/G |
| Function | Major viral capsid protein that encapsidates the viral genome. Binds to the 5' end of the genomic RNA. |
| Molecular Weight | Theoretical: 13.5 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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