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IL-31RA Protein, Mouse, Recombinant (E. coli, His)

(Synonyms: ZcytoR17, Novel cytokine receptor 10 (NR10), Interleukin-31 receptor subunit alpha, IL-31R-alpha, IL-31RA, Il31ra, IL-31R subunit alpha, IL-31 receptor subunit alpha, Gp130-like monocyte receptor (Gp130-like receptor), GLM-R (mGLM-R), Glmr) Copy Product Info

Synonyms: ZcytoR17, Novel cytokine receptor 10 (NR10), Interleukin-31 receptor subunit alpha, IL-31R-alpha, IL-31RA, Il31ra, IL-31R subunit alpha, IL-31 receptor subunit alpha, Gp130-like monocyte receptor (Gp130-like receptor), GLM-R (mGLM-R), Glmr

Catalog No. TMPH-02740 Copy Product Info
Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. IL-31R alpha Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 59.2 kDa and the accession number is Q8K5B1.
IL-31RA Protein, Mouse, Recombinant (E. coli, His)
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Pack SizePriceUSA StockGlobal StockQuantity
5 μg$12920 days20 days
10 μg$21620 days20 days
20 μg$36020 days20 days
50 μg$54320 days20 days
100 μg$74520 days20 days
200 μg$1,07020 days20 days
500 μg$1,73020 days20 days
1 mg$2,53020 days20 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity. Mediates IL31-induced itch, probably in a manner dependent on cation channels TRPA1 and TRPV1. Positively regulates numbers and cycling status of immature subsets of myeloid progenitor cells in bone marrow in vivo and enhances myeloid progenitor cell survival in vitro. IL-31R alpha Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 59.2 kDa and the accession number is Q8K5B1.
Species
Mouse
Expression System
E. coli
TagN-6xHis
Accession NumberQ8K5B1
Amino AcidVLPTKPENISCVFYFDRNLTCTWRPEKETNDTSYIVTLTYSYGKSNYSDNATEASYSFPRSCAMPPDICSVEVQAQNGDGKVKSDITYWHLISIAKTEPPIILSVNPICNRMFQIQWKPREKTRGFPLVCMLRFRTVNSSHWTEVNFENCKQVCNLTGLQAFTEYVLALRFRFNDSRYWSKWSKEETRVTMEEVPHVLDLWRILEPADMNGDRKVRLLWKKARGAPVLEKTFGYHIQYFAENSTNLTEINNITTQQYELLLMSQAHSVSVTSFNSLGKSQEAILRIPDVHEKTFQYIKSMKAYIAEPLLVVNWQSSIPAVDTWIVEWLPEAAMSKFPALSWESVSQVTNWTIEQDKLKPFTCYNISVYPVLGHRVGEPYSIQAYAKEGTPLKGPETRVENIGLRTATITWKEIPKSARNGFINNYTVFYQAEGGKELSKTVNSHALQCDLESLTRRTSYTVWVMASTRAGGTNGVRINFKT
Construction19-499 aa
Protein Purity
> 85% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsZcytoR17, Novel cytokine receptor 10 (NR10), Interleukin-31 receptor subunit alpha, IL-31R-alpha, IL-31RA, Il31ra, IL-31R subunit alpha, IL-31 receptor subunit alpha, Gp130-like monocyte receptor (Gp130-like receptor), GLM-R (mGLM-R), Glmr
Research Background
Chemical Properties
Molecular Weight59.2 kDa (predicted)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Keywords

Related Tags: IL-31RA Protein, Mouse, Recombinant (E. coli, His) chemical structure | IL-31RA Protein, Mouse, Recombinant (E. coli, His) molecular weight