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Anti-PRDM5 Antibody (2C105)
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Catalog No. TMAC-03414
Alias PRDM5_HUMAN, PRDM5 protein, PRDM 5, PR domain-containing protein 5, PR domain zinc finger protein 5, PR domain containing protein 5, PR domain containing 5, PFM2, PFM 2, BCS2
Anti-PRDM5 Antibody (2C105) is a Mouse antibody targeting PRDM5. Anti-PRDM5 Antibody (2C105) can be used in FCM,ICC,WB.
Anti-PRDM5 Antibody (2C105)
Anti-PRDM5 Antibody (2C105)
😃Good
Catalog No. TMAC-03414Alias PRDM5_HUMAN, PRDM5 protein, PRDM 5, PR domain-containing protein 5, PR domain zinc finger protein 5, PR domain containing protein 5, PR domain containing 5, PFM2, PFM 2, BCS2
Anti-PRDM5 Antibody (2C105) is a Mouse antibody targeting PRDM5. Anti-PRDM5 Antibody (2C105) can be used in FCM,ICC,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $427 | 7-10 days |
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Product Introduction
Bioactivity
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Antigen Details
Chemical Properties
| Description | Anti-PRDM5 Antibody (2C105) is a Mouse antibody targeting PRDM5. Anti-PRDM5 Antibody (2C105) can be used in FCM,ICC,WB. |
| Synonyms | PRDM5_HUMAN, PRDM5 protein, PRDM 5, PR domain-containing protein 5, PR domain zinc finger protein 5, PR domain containing protein 5, PR domain containing 5, PFM2, PFM 2, BCS2 |
| Clone | 2C105 |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Western blot analysis of PRDM5 on human PRDM5 recombinant protein using anti-PRDM5 antibody at 1/1,000 dilution. 2. Western blot analysis of PRDM5 on HEK293 (1) and PRDM5-hIgGFc transfected HEK293 (2) cell lysate using anti-PRDM5 antibody at 1/1,000 dilution. 3. ICC staining PRDM5 (green) and Actin filaments (red) in MCF-7 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. Flow cytometric analysis of Hela cells with PRDM5 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).     |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | A cDNA of PRDM5 was isolated based upon its homology to the PR domain of PRDM2. The gene encodes an open reading frame of 630 amino acids and contains a PR domain in the NH-terminal region followed by 16 zinc finger motifs. Through radiation hybrid analysis, PRDM5 was mapped to human chromosome 4q27, a region thought to contain tumor suppressor genes for ovarian, breast, lung, liver, colon, and other cancers. The gene has a CpG island promoter and is silenced in human breast, ovarian, and liver cancers. Upon infection of tumor cells, a recombinant adenovirus expressing PRDM5 causes G2/M arrest and apoptosis, suggesting that inhibition of PRDM5 may be involved in carcinogenesis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 73 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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