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Pyribencarb

Name: Pyribencarb
Brand: TargetMol
SKU: T37069
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T37069Cas No. 799247-52-2

Alias ZINC43065336

Pyribencarb, a benzylcarbamate-type fungicide, exhibits broad-spectrum activity against various plant pathogenic fungi. Acting as a potent Qo inhibitor of cytochrome b, Pyribencarb demonstrates particular efficacy against Botrytis cinerea and Sclerotinia sclerotiorum.

Pyribencarb

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Purity: 99.75%

Catalog No. T37069Alias ZINC43065336Cas No. 799247-52-2

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$38	-	In Stock
25 mg	$64	-	In Stock
50 mg	$98	-	In Stock
1 mL x 10 mM (in DMSO)	$29	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.75%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Pyribencarb, a benzylcarbamate-type fungicide, exhibits broad-spectrum activity against various plant pathogenic fungi. Acting as a potent Qo inhibitor of cytochrome b, Pyribencarb demonstrates particular efficacy against Botrytis cinerea and Sclerotinia sclerotiorum.
In vitro	Pyribencarb effectively suppresses succinate-cytochrome c reductase (SCR) activities in Botrytis cinerea (cucumber gray mold), Corynespora cassiicola (leaf spot), and decylubiquinol-cytochrome c reductase (UCR) in B. cinerea, demonstrating uncompetitive inhibition of B. cinerea's UCR with a substrate-dependent inhibition constant of 13 nM[1]. Its action targets cytochrome b within complex III of the electron transport chain's respiratory system. Compared to strobilurin fungicides, pyribencarb shows relatively less inhibitory strength on SCR activities in plants, rats, and carp[1].
Synonyms	ZINC43065336

Chemical Properties

Molecular Weight	361.82
Formula	C₁₈H₂₀ClN₃O₃
Cas No.	799247-52-2
Smiles	C(=N\OCC=1N=C(C)C=CC1)(\C)/C2=CC(CNC(OC)=O)=C(Cl)C=C2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (248.74 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (9.12 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7638 mL	13.8190 mL	27.6381 mL	138.1903 mL
5 mM	0.5528 mL	2.7638 mL	5.5276 mL	27.6381 mL
10 mM	0.2764 mL	1.3819 mL	2.7638 mL	13.8190 mL
20 mM	0.1382 mL	0.6910 mL	1.3819 mL	6.9095 mL
50 mM	0.0553 mL	0.2764 mL	0.5528 mL	2.7638 mL
100 mM	0.0276 mL	0.1382 mL	0.2764 mL	1.3819 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc