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Pinocembrin 7-O-[4",6"-(S)-HHDP]-β-D-glucoside

🥰Excellent
Catalog No. TN8056Cas No. 205370-58-7

Pinocembrin 7-O-[4",6"-(S)-HHDP]-β-D-glucoside, is a complex polyphenol compound that has been shown to exhibit modest antiproliferative effects in platelet-derived growth factor (PDGF)-induced HSC-T6 hepatic stellate cells with an IC50 of 200 μM. further experiments confirm that Pinocembrin 7-O-[4",6"-(S)-HHDP]-β-D-glucoside possesses a more remarkable anti-proliferative effect specifically against activated hepatic stellate cells (HSCs), which are key drivers of liver fibrosis.

Pinocembrin 7-O-[4",6"-(S)-HHDP]-β-D-glucoside

Pinocembrin 7-O-[4",6"-(S)-HHDP]-β-D-glucoside

🥰Excellent
Catalog No. TN8056Cas No. 205370-58-7
Pinocembrin 7-O-[4",6"-(S)-HHDP]-β-D-glucoside, is a complex polyphenol compound that has been shown to exhibit modest antiproliferative effects in platelet-derived growth factor (PDGF)-induced HSC-T6 hepatic stellate cells with an IC50 of 200 μM. further experiments confirm that Pinocembrin 7-O-[4",6"-(S)-HHDP]-β-D-glucoside possesses a more remarkable anti-proliferative effect specifically against activated hepatic stellate cells (HSCs), which are key drivers of liver fibrosis.
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5 mg$483In Stock
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Bioactivity
Description
Pinocembrin 7-O-[4",6"-(S)-HHDP]-β-D-glucoside, is a complex polyphenol compound that has been shown to exhibit modest antiproliferative effects in platelet-derived growth factor (PDGF)-induced HSC-T6 hepatic stellate cells with an IC50 of 200 μM. further experiments confirm that Pinocembrin 7-O-[4",6"-(S)-HHDP]-β-D-glucoside possesses a more remarkable anti-proliferative effect specifically against activated hepatic stellate cells (HSCs), which are key drivers of liver fibrosis.
Chemical Properties
Molecular Weight720.59
FormulaC35H28O17
Cas No.205370-58-7
SmilesO=C1OCC2OC(OC3=CC(O)=C4C(=O)CC(OC4=C3)C=5C=CC=CC5)C(O)C(O)C2OC(=O)C6=CC(O)=C(O)C(O)=C6C=7C(O)=C(O)C(O)=CC17
ColorTransparent
AppearanceOil
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
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