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Anti-CD93 Polyclonal Antibody is a Rabbit antibody targeting CD93. Anti-CD93 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $220 | 7-10 days | |
100 μL | $374 | 7-10 days | |
200 μL | $529 | 7-10 days |
Description | Anti-CD93 Polyclonal Antibody is a Rabbit antibody targeting CD93. Anti-CD93 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P. |
Synonyms | MXRA4, ECSM3, dJ737E23.1, CDw93, CD93, C1qRp, C1QR1, C1qR(p), C1qR, C1q/MBL/SPA receptor |
Ig Type | IgG |
Reactivity | Human (predicted:Mouse,Rat,Dog) |
Verified Activity | 1. Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-CD93 Polyclonal Antibody, Unconjugated (TMAB-00399) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. 2. Tissue/cell: human kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer (0.01M, pH6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Incubation: Anti-CD93 Polyclonal Antibody, Unconjugated (TMAB-00399) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody and DAb staining. |
Application | |
Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
Antibody Type | Polyclonal |
Host Species | Rabbit |
Subcellular Localization | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. Not expressed in cells of lymphoid origin. |
Construction | Polyclonal Antibody |
Purification | Protein A purified |
Appearance | Liquid |
Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Concentration | 1 mg/mL |
Research Background | The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q, but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin, a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton. [provided by RefSeq, Jul 2008]. |
Immunogen | KLH conjugated synthetic peptide: human CD93 |
Antigen Species | Human |
Gene Name | CD93 |
Gene ID | |
Protein Name | Complement component C1q receptor |
Uniprot ID | |
Biology Area | Endothelial Cell Markers,Adhesion,Surface Molecules |
Function | Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion. |
Molecular Weight | Theoretical: 70 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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