BTLA Protein, Human, Recombinant (isoform2, His)

Name: BTLA Protein, Human, Recombinant (isoform2, His)
Brand: TargetMol
SKU: TMPY-07085
Rating: 4.5 (1 reviews)

(Synonyms: CD272, BTLA1) Copy Product Info

Synonyms: CD272, BTLA1

Catalog No. TMPY-07085 Copy Product Info

BTLA Protein, Human, Recombinant (aa 1-134, His) is expressed in HEK293 Cells. The accession number is Q7Z6A9-2.

BTLA Protein, Human, Recombinant (isoform2, His)

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Pack Size	Price	USA Stock	Global Stock
5 µg	$155	7-10 days	7-10 days
10 µg	$247	7-10 days	7-10 days
20 µg	$395	7-10 days	7-10 days
50 µg	$710	7-10 days	7-10 days
100 µg	$1,140	7-10 days	7-10 days
200 µg	$1,820	7-10 days	7-10 days
500 µg	$3,270	7-10 days	7-10 days
1 mg	$5,240	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Immobilized BTLA Protein, Human, Recombinant (aa 1-134, His) (Cat#TMPY-07085) at 2 μg/ml (100 μl/well) can bind Recombinant Mouse HVEM/TNFRSF14 Protein (His & Fc Tag), the EC50 is 11-33 ng/mL.
Description	BTLA Protein, Human, Recombinant (aa 1-134, His) is expressed in HEK293 Cells. The accession number is Q7Z6A9-2.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q7Z6A9-2
Construction	A DNA sequence encoding the Human BTLA (NP_001078826.1) (Met1-Thr134) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity	≥ 95% as determined by SDS-PAGE. ≥ 95% as determined by SEC-HPLC.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Please refer to the lot-specific COA.
Synonyms	CD272, BTLA1
Research Background	BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeutic promise. BTLA is crucial to understand the mechanism(s) of action of these antibodies before attempting clinical applications. BTLA is not expressed by naive T cells, but it is induced during activation and remains expressed on T helper type 1 (T(H)1) but not T(H)2 cells. BTLA is a third inhibitory receptor on T lymphocytes with similarities to cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) and programmed death 1 (PD-1).Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint TargetsImmunotherapyTargeted Therapy

Chemical Properties

Molecular Weight

13.47 kDa (predicted); 30 kDa (reducing contition)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.