POT-4 acetate

Name: POT-4 acetate
Brand: TargetMol
SKU: T9695L
Rating: 4.5 (1 reviews)

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Catalog No. T9695L

Alias POT-4 acetate (934461-40-2 free base)

POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.

POT-4 acetate

😃Good

Catalog No. T9695LAlias POT-4 acetate (934461-40-2 free base)

POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$187	Inquiry	Inquiry
5 mg	$383	Inquiry	Inquiry
10 mg	$597	Inquiry	Inquiry
25 mg	$1,217	Inquiry	Inquiry
50 mg	$1,895	Inquiry	Inquiry
100 mg	$2,747	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	POT-4 acetate inhibits Complement C3 activation. POT-4 acetate can be used for studies about age-related macular degeneration.
In vitro	POT-4 acetate, a compstatin derivative, binds to C3 and prevents cleavage to its active fragments C3a and C3b[1].
Synonyms	POT-4 acetate (934461-40-2 free base)

Chemical Properties

Molecular Weight	1687.9
Formula	C₇₄H₁₀₆N₂₂O₂₀S₂
Sequence	Ile-Cys(1)-Val-Trp(Me)-Gln-Asp-Trp-Gly-Ala-His-Arg-Cys(1)-Thr
Sequence Short	ICVXQDWGAHRCT

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc