This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
PRMT5-IN-28
Catalog No. T79035 CAS
2242753-66-6
PRMT5-IN-28 (compound 36) serves as an inhibitor of the protein arginine methyltransferase 5 (PRMT5) enzyme, which is implicated in various cellular processes including gene transcription, mRNA splicing, DNA repair, protein cellular localization, cell fate determination, and signal transduction. Dysregulated PRMT5 activity contributes to oncogenesis by promoting cancer cell proliferation, apoptosis resistance, invasion, metastasis, and impacting immune evasion [1].
All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
PRMT5-IN-28 (compound 36) serves as an inhibitor of the protein arginine methyltransferase 5 (PRMT5) enzyme, which is implicated in various cellular processes including gene transcription, mRNA splicing, DNA repair, protein cellular localization, cell fate determination, and signal transduction. Dysregulated PRMT5 activity contributes to oncogenesis by promoting cancer cell proliferation, apoptosis resistance, invasion, metastasis, and impacting immune evasion [1].
Molecular Weight
406.82
Formula
C18H19ClN4O5
CAS No.
2242753-66-6
Storage
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Method for preparing DMSO master liquid: mg
drug pre-dissolved in μL DMSO (Master liquid concentration
mg/mL),
Method for preparing in vivo formulation:Take μL
DMSO master liquid, next add μL PEG300, mix and clarify, next add μL
Tween 80,mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation:Take μL
DMSO master liquid, next add μL Corn oil,mix and clarify.
Note:
Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.