IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)

Name: IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
Brand: TargetMol
SKU: TMPK-00515
Rating: 4.5 (1 reviews)

(Synonyms: Interleukin-1 β, Interleukin-1 beta, IL-1β, IL1F2, IL-1BETA, IL-1B, IL1B, IL-1 β/IL-1F2, IL-1 β, IL-1 beta) Copy Product Info

Synonyms: Interleukin-1 β, Interleukin-1 beta, IL-1β, IL1F2, IL-1BETA, IL-1B, IL1B, IL-1 β/IL-1F2, IL-1 β, IL-1 beta

Catalog No. TMPK-00515 Copy Product Info

Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.33 kDa and the accession number is A0A2K5VDC7.

IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)

Pack Size	Price	USA Stock	Global Stock
5 µg	$58	7-10 days	7-10 days
10 µg	$92	7-10 days	7-10 days
20 µg	$148	7-10 days	7-10 days
50 µg	$289	7-10 days	7-10 days
100 µg	$487	7-10 days	7-10 days
200 µg	$883	7-10 days	7-10 days
500 µg	$1,950	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Human IL-1 RII, hFc Tag captured on CM5 Chip via Protein A can bind Cynomolgus IL-1 Beta, His Tag with an affinity constant of 1.40 nM as determined in SPR assay.
Description	Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells. IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 18.33 kDa and the accession number is A0A2K5VDC7.
Species	Cynomolgus
Expression System	E. coli
Tag	C-His
Accession Number	A0A2K5VDC7
Construction	Ala117-Ser268
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 100 mM L-arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	Interleukin-1 β, Interleukin-1 beta, IL-1β, IL1F2, IL-1BETA, IL-1B, IL1B, IL-1 β/IL-1F2, IL-1 β, IL-1 beta
Research Background	Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1 signaling activates innate immune cells including antigen presenting cells, and drives polarization of CD4 T cells towards T helper type (Th) 1 and Th17 cells.

Chemical Properties

Molecular Weight

18.33 kDa (predicted) same as Tris-Bis PAGE result.

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Tech Support

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Keywords

Interleukin-1 bIL-1 b

Related Tags: IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) chemical structure | IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) molecular weight